Evidence map›Paper›PMID 41634202›Full record

ArticleNature2026

Ontogeny and transcriptional regulation of Thetis cells.

Yoselin A Paucar Iza, Tyler Park, Eliyambuya Baker, Gayathri Shibu, Tilman Hoelting, Greyson Feather, Anushka Yadav, Yollanda Franco Parisotto, Zihan Zhao, Blossom Akagbosu and 8 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Yoselin A Paucar IzaHoward Hughes Medical Institute, New York, NY, USA.
Tyler ParkComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-1246-1544
Eliyambuya BakerImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gayathri ShibuImmunology and Microbial Pathogenesis Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA.
Tilman HoeltingImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-5598-7330
Greyson FeatherImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anushka YadavImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-4333-6028
Yollanda Franco ParisottoHoward Hughes Medical Institute, New York, NY, USA.
Zihan ZhaoImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Blossom AkagbosuImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marc Elosua BayesImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Logan FisherImmunology and Microbial Pathogenesis Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA.ORCID http://orcid.org/0000-0003-4680-1527
Lucas M JamesDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-0499-9299
Jianping MaImmunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA.
Benjamin D PhilpotDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-2746-9143
Behdad AfzaliImmunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA.
Christina LeslieComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-4571-5910
Chrysothemis C BrownHoward Hughes Medical Institute, New York, NY, USA. brownc10@mskcc.org.ORCID http://orcid.org/0000-0002-5834-926X

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Deciphering the Genomics of Gene Network Regulation of T Cell and Fibroblast States in Autoimmune InflammationU01HG012103 · NHGRI · SLOAN-KETTERING INST CAN RESEARCH · PI Christina S Leslie, Alexander Y Rudensky · 2021 to 2026
$7.5M
Acceptance of non-self: Decoding intestinal immune tolerance during early lifeDP2AI171116 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI Chrysothemis Brown · 2022 to 2026
$2.7M
NCI NIH HHS P30 CA008748NHGRI NIH HHS U01 HG012103NIAID NIH HHS DP2 AI171116
6 · The paper itself

Abstract

Thetis cells (TCs) are a recently identified lineage of RORγt

Indexed as

Cell LineageGene Expression RegulationLymphoid TissueTranscription, GeneticAnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCell DifferentiationDendritic CellsFemaleImmune ToleranceMaleMiceMice, Inbred C57BLNuclear Receptor Subfamily 1, Group F, Member 3Proto-Oncogene ProteinsTrans-ActivatorsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsNuclear Receptor Subfamily 1, Group F, Member 3Proto-Oncogene ProteinsRorc protein, mouseTcf4 protein, mouseTrans-ActivatorsTranscription Factor 4

Identifiers

PMID41634202
PMCPMC13171621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.