Evidence map›Paper›PMID 41634113›Full record

ArticleScientific reports2026

Phytochemical composition and antimicrobial activity of Matricaria chamomilla ethanolic extracts against clinical bacterial isolates in Ibb City, Yemen.

Abeer Esmail, Asmaa Hassan, Khadeja Almuntaser, Nasibh Alashari, Nosiubah Alkadry, Reem Alnahi, Halah Alhagwa, Rehab Hamza, Nadia Alhubaishy, Ammar Al-Farga and 1 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abeer EsmailMedical Laboratories Department, Faculty of Medicine and Health Sciences, Ibb University, Ibb City, Yemen. abeer.a.esmail@gmail.com.
Asmaa HassanDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen. Smaalwady788@gmail.com.
Khadeja AlmuntaserDepartment of Pharmacy, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Nasibh AlashariDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Nosiubah AlkadryDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Reem AlnahiDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Halah AlhagwaDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Rehab HamzaDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Nadia AlhubaishyDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.
Ammar Al-FargaDepartment of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Tasneem AlnuzailiDepartment of Medical Laboratories, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyze the phytochemical constituents and evaluate the antimicrobial effects of ethanolic extracts from Matricaria chamomilla (chamomile) leaves and flowers against clinical bacterial isolates collected from Ibb City, Yemen. Phytochemical screening revealed presence of alkaloids, tannins, sterols, and terpenoids in both leaves and flowers, while flavonoids, glycosides, saponins, and amino acids were absent. Antibacterial activity was assessed using inhibition zone diameters against pathogens including Staphylococcus aureus, Escherichia coli, Salmonella spp., and Pseudomonas aeruginosa. The extracts showed significant antimicrobial activity, especially against S. aureus, with leaf extract showing a 24 mm inhibition zone and flower extract 15 mm. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests confirmed the potent bactericidal effects at low extract concentrations (100 mg/mL). These findings underscore the therapeutic potential of M. chamomilla as a natural antimicrobial agent relevant to combating bacterial infections, especially in the local Yemeni context. Further studies are recommended to isolate active compounds and evaluate mechanisms of action.

Indexed as

Anti-Bacterial AgentsBacteriaMatricariaPhytochemicalsPlant ExtractsEscherichia coliEthanolFlowersHumansMicrobial Sensitivity TestsPlant LeavesPseudomonas aeruginosaStaphylococcus aureusYemenAnti-Bacterial AgentsEthanolPhytochemicalsPlant ExtractsAntimicrobial activityChamomileMatricaria chamomilla(MBC)(MIC)PhytochemicalsYemen

Identifiers

PMID41634113
PMCPMC12920616

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