Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
27 authors.
Lewis J WilliamsSchool of Life Sciences, University of Essex, Colchester, UK.
Jos J A G KampsDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK.ORCID 0000-0001-8646-1796
Adrian M V BrânzanicFaculty of Chemistry and Chemical Engineering and INSPIRE Platform InfoBioNano4Health & Biomedical Imaging, Babeș-Bolyai University, Cluj-Napoca, Romania.ORCID 0000-0002-4166-0131
Maria LeheneFaculty of Chemistry and Chemical Engineering and INSPIRE Platform InfoBioNano4Health & Biomedical Imaging, Babeș-Bolyai University, Cluj-Napoca, Romania.ORCID 0000-0003-0768-2342
Kristoffer J M LundgrenDivision of Computational Chemistry, Lund University, Chemical Centre, Sweden.ORCID 0009-0002-2611-7883
Ulf RydeDivision of Computational Chemistry, Lund University, Chemical Centre, Sweden.ORCID 0000-0001-7653-8489
Kuntal ChatterjeeMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Margaret D DoyleMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Philipp S SimonMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-2859-4475
Hiroki MakitaMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-4968-914X
Aaron S BrewsterMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-0908-7822
Marina LučićSchool of Life Sciences, University of Essex, Colchester, UK.
Michael T WilsonSchool of Life Sciences, University of Essex, Colchester, UK.
Pierre AllerDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK.ORCID 0000-0002-1793-7030
Juan Sanchez-WeatherbyDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK.
Leland GeeLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.ORCID 0000-0002-5817-3997
Sebastian DeheLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.ORCID 0000-0002-9206-9106
Sandra MousLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.ORCID 0000-0002-3532-5978
Junko YanoMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0001-6308-9071
Vittal K YachandraMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-3983-7858
Michael A HoughSchool of Life Sciences, University of Essex, Colchester, UK. Michael.Hough@diamond.ac.uk.
Allen M OrvilleDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK. allen.orville@diamond.ac.uk.ORCID 0000-0002-7803-1777
Jan F KernMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jfkern@lbl.gov.ORCID 0000-0002-7272-1603
Radu L Silaghi-DumitrescuFaculty of Chemistry and Chemical Engineering and INSPIRE Platform InfoBioNano4Health & Biomedical Imaging, Babeș-Bolyai University, Cluj-Napoca, Romania. radu.silaghi@ubbcluj.ro.ORCID 0000-0003-3038-7747
Jonathan A R WorrallSchool of Life Sciences, University of Essex, Colchester, UK. jworrall@essex.ac.uk.ORCID 0000-0002-1863-834X
Funding
Biological Spectroscopy and Crystallography Using an X-ray Free Electron Laser - Supplemental EquipmentR01GM110501 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Junko Yano · 2014 to 2026
$4.8M
High throughput sample delivery method for time resolved studies of enzyme reactions with X-ray and complementary techniquesR01GM126289 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI KERN, JAN F · 2017 to 2025
$4.6M
DIALS: supporting structural biology through open source diffraction processing softwareR24GM154040 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Aaron Samuel Brewster · 2024 to 2026
$3.7M
Diamond Light Source STU0436NIGMS NIH HHS R01 GM110501NIGMS NIH HHS R01 GM126289NIGMS NIH HHS R24 GM154040RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/W001950/1Royal Society RSWF/R2/182017Wellcome Trust (Wellcome) 210734/Z/18/Z
6 · The paper itself
Abstract
The use of X-ray structures to determine and interpret the ferryl iron-oxygen bond order in molecular oxygen-activating heme enzymes has, in the past, been controversial. This has mainly stemmed from the susceptibility of ferryl species to X-ray-induced electronic state changes. In this work we establishe using time-resolved serial femtosecond X-ray crystallography (tr-SFX) on a dye-decolourising peroxidase that the ferryl intermediate species (Compounds I and II) captured following in situ mixing of microcrystals with H
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Can ferric-oxyl excited states explain elongated iron-oxygen bonds in heme peroxidase catalytic intermediates? · full record | OpenQuestion