Article in International journal of oral science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Rajnikant Dilip Raut *Translational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0000-0001-6963-5889
Chumki Choudhury *Translational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0009-0004-0412-7161
Faiza AliTranslational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0009-0004-9535-3729
Amit Kumar ChakrabortyTranslational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0000-0001-7455-6579
Mohammed Moeeduddin AhmedTranslational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.
Cheyleann Del Valle Ponce De LeonTranslational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0000-0001-6383-9602
Harshal V ModhRestorative Sciences & Biomaterials, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0009-0001-5582-4977
Pushkar MehraDepartment of Oral and Maxillofacial Surgery, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0000-0002-9661-0289
Yuwei FanRestorative Sciences & Biomaterials, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.ORCID 0000-0001-8477-8458
Alejandro AlmarzaDepartment of Oral and Craniofacial Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-4602-9258
Manish V BaisTranslational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA. bmanish@bu.edu.ORCID 0000-0003-4198-7377
Funding
Mechanism of LSD1 Function and Its Therapeutic Application for Progressive Oral MalignancyR01DE031413 · NIDCR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Manish Bais · 2022 to 2026
$2.7M
NIDCR NIH HHS R01 DE031413
6 · The paper itself
Abstract
Temporomandibular joint osteoarthritis (TMJ-OA) affects a significant proportion of the population worldwide. However, there has been no substantial progress in the development of FDA-approved drugs for treatment due to a lack of understanding of the specific factors regulating key TMJ-OA molecular mechanisms. Lysyl Oxidase-Like-2 (LOXL2) promotes knee joint cartilage protection and is downregulated in a TMJ-OA animal model. We evaluated the role of LOXL2 in TMJ cartilage, its molecular mechanism, and gene networks using in vivo Loxl2 knockout mice (Acan-Cre; Loxl2
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
LOXL2 deletion triggers TMJ osteoarthritis, while overexpression protects it from NF-κB-induced chondrocyte apoptosis. · full record | OpenQuestion