Evidence map›Paper›PMID 41633804›Full record

ArticleBritish journal of sports medicine2026

Active commuting and atherosclerosis in a population-based sample of middle-aged adults: the Swedish CArdioPulmonary bioImage study (SCAPIS).

Peter Edholm, Patrik Wennberg, Marcel Ballin, Carl-Johan Östgren, Bledar Daka, Daniel Berglind, Cecilia Lenander, Viktor H Ahlqvist, Karin Rådholm, Pontus Henriksson and 1 more

Abstract read
In one paragraph

Article in British journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter EdholmDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden peter.edholm@hh.se.ORCID http://orcid.org/0000-0002-5401-9255
Patrik WennbergDepartment of Public Health and Clinical Medicine, Umeå Universitet, Umeå, Västerbotten County, Sweden.
Marcel BallinDepartment of Public Health and Caring Sciences, Clinical Geriatrics, Uppsala Universitet, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-9638-7208
Carl-Johan ÖstgrenDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Bledar DakaSchool of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden.
Daniel BerglindDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-0616-7779
Cecilia LenanderDepartment of Clinical Sciences in Malmö, Centre for Primary Health Care Research, Lund University, Lund, Sweden.
Viktor H AhlqvistInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-1383-3194
Karin RådholmDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Pontus HenrikssonDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0003-2482-7048
Ángel Herraiz-AdilloDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between active commuting and atherosclerosis in middle age using state-of-the-art coronary CT angiography (CCTA).

methodsThis cross-sectional study used data from the Swedish CArdioPulmonary bioImage Study (SCAPIS) and included 23 722 randomly recruited individuals aged 50-64 years from six different regions in Sweden. The exposure was commuting mode, assessed using self-reported questionnaires and categorised as year-round walking and/or cycling (active commuting), commuting by bus/train, commuting by car or mixed commuting patterns. The outcome was atherosclerosis, evaluated using CCTA for coronary stenosis and coronary artery calcium (CAC) score and ultrasound for carotid plaques. Associations were analysed using multivariate binomial logistic regression models.

resultsAfter adjusting for confounders (age, sex, SCAPIS site, education, occupational physical activity and leisure time exercise habits, sleep, diet and smoking habits), active commuting was associated with lower odds of coronary stenosis (OR 0.87; 95% CI 0.80 to 0.94) and a CAC score ≥1 Agatston units (OR 0.93; 95% CI 0.86 to 1.00), as compared with car commuting. No associations were observed between active commuting and the presence of carotid plaques (OR 0.97; 95% CI 0.90 to 1.03). When stratified, the inverse association with coronary stenosis appeared to be somewhat stronger for cycling (OR 0.86; 95% CI 0.78 to 0.95) than for walking (OR 0.89; 95% CI 0.79 to 1.01).

conclusionUsing advanced CCTA imaging in a large, randomly selected sample of middle-aged adults, we show for the first time that coronary atherosclerosis is less common in active commuters, particularly those cycling, compared with car commuters. While this indicates that active commuting might be a potential preventive measure to reduce atherosclerosis and subsequent cardiovascular disease, further causal analyses are needed to confirm our findings.

Indexed as

AtherosclerosisBicyclingCoronary Artery DiseaseTransportationWalkingComputed Tomography AngiographyCoronary AngiographyCoronary StenosisCross-Sectional StudiesFemaleHumansMaleMiddle AgedSwedenBicyclingCardiovascular DiseasesPhysical activityPublic healthWalking

Identifiers

PMID41633804
PMCPMC13018793

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.