ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2026
[Microbial communities in extraradicular infections of post-treatment apical periodontitis without or with sinus tracts].
Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the composition and structure of extraradicular bacterial communities in periapical lesions of teeth with post-treatment apical periodontitis (PoAP) between cases with and without sinus tracts.
methodsPatients requiring apical surgery were recruited from the Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology. Periapical lesion samples were collected from teeth with sinus tracts and without sinus tracts during apical microsurgery. The remaining lesion samples were submitted for pathological examination. Following the extraction of the bacterial DNA, the V3-V4 region of the bacterial 16S rRNA gene was subjected to high-throughput sequencing using Illumina NovaSeq 6000. Bioinformatics analysis was performed using QIIME2 software. α diversity indices (Shannon, Simpson, Chao1) were calculated, and intergroup differences were analyzed using Wilcoxon test. β diversity was assessed by principal coordinate analysis based on Weighted Unifrac test, and community composition differences were analyzed with permutational multivariate analysis of variance (PERMANOVA). Differences in relative abundance between the groups were compared using the Wilcoxon test, followed by Benjamini-Hochberg false discovery rate (FDR) correction to convert
resultsA total of 66 subjects were enrolled, including 21 male and 45 female patients, with a mean age of (33.91±9.16) years. Three subjects each had two teeth enrolled. In total, 69 teeth were included. These teeth included 47 cases without sinus tracts and 22 cases with sinus tracts. No significant differences were observed between the two groups in the distribution of obturation quality or pathological types (
conclusionThe extraradicular bacterial community structure significantly differs between PoAP with and without sinus tracts.
Indexed as
Identifiers
41633584PMC12872361What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.