ArticleJournal of aging and physical activity2026
Associations of Accelerometer-Measured Physical Activity and Sedentary Behavior With Incident Clinical Osteoporotic Fractures Among Older Women: The Objective Physical Activity and Cardiovascular Health Study.
Article in Journal of aging and physical activity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesWomen 65 and older experience nearly three-fourths of the 2 million osteoporotic fractures annually in the United States. We investigated associations of accelerometer-measured total physical activity, light physical activity, moderate-to-vigorous physical activity (MVPA), steps, total sitting time, and mean sitting bout duration with incident osteoporotic fracture.
methodsWomen from the Objective Physical Activity and Cardiovascular Health cohort (N = 6,122; mean age: 78.7; SD: 6.7) without prior hip fracture wore the ActiGraph GT3X+ up to 7 days and were followed up to 8 years for incident osteoporotic fractures (n = 982). Cox regression models estimated hazard ratios and 95% confidence intervals (CI) additionally containing age, race/ethnicity, education, alcohol, smoking, height, weight, falls, physical functioning, diabetes, thiazide use, and anti-osteoporosis medication use.
resultsMultivariable HRs (95% CI) were 1 (ref), 1.10 [0.93, 1.31], 0.93 [0.77, 1.13], and 0.87 [0.70, 1.07] across MVPA minutes/quartiles (p-trend = .03) and 1 (ref), 1.10 [0.90, 1.33], 1.21 [1.00, 1.47], and 1.27 [1.04, 1.57] across total sitting time quartiles (p-trend = .02). The hazard ratios (95% CI) for a one-SD increment in MVPA (33 min/day) and total sitting time (103 min/day) were 0.92 [0.85, 0.99] and 1.09 [1.01, 1.18], respectively. The hazard ratios (95% CI) for MVPA and osteoporotic fracture was 0.82 [0.73, 0.93] among women not using anti-osteoporosis medication and 1.06 [0.90, 1.24] among women using anti-osteoporosis medication (p-interaction = .02).
conclusionsMore MVPA and less total sitting time, but not other accelerometer measures, were associated with lower osteoporotic fracture risk. Significance/Implications: These data support interventions and physical activity guidelines aimed at promoting moderate- or vigorous-intensity movement and decreased sitting for osteoporotic fracture prevention.
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