Evidence map›Paper›PMID 41632842›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A factor integrating transcription and repression of surface antigen genes in African trypanosomes.

María Agustina Berazategui, Ione Goodwin, Lianne I M Lansink, Keith Gull, Gloria Rudenko, Jack D Sunter, Joana R C Faria, Richard J Wheeler, Calvin Tiengwe

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Microbiology spectrum · 2026
    Article
  2. A factor integrating transcription and repression of surface antigen genes in African trypanosomes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

María Agustina BerazateguiDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0009-0007-8196-3536
Ione GoodwinDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0009-0008-5635-0735
Lianne I M LansinkDepartment of Biology, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0003-1965-1287
Keith GullDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0001-6954-9569
Gloria RudenkoDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0003-1884-4933
Jack D SunterDepartment of Biological and Medical Sciences, Oxford Brookes University, Oxford OX3 0BP, United Kingdom.ORCID 0000-0002-2836-9622
Joana R C FariaDepartment of Biology, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0001-6274-8143
Richard J WheelerSchool of Biological Sciences, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, Scotland, United Kingdom.ORCID 0000-0002-4270-8360
Calvin TiengweDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0002-3742-6502

Funding

Wellcome TrustWellcome Trust (WT) 208780/Z/17/ZWellcome Trust (WT) 211075/Z/18/ZWellcome Trust (WT) 212211/A/18/ZWellcome Trust (WT) 222573/Z/21/Z
6 · The paper itself

Abstract

Antigenic variation in

Indexed as

Antigens, SurfaceProtozoan ProteinsTranscription, GeneticTrypanosoma brucei bruceiAntigenic VariationGene Expression RegulationRNA InterferenceRNA Polymerase IVariant Surface Glycoproteins, TrypanosomaAntigens, SurfaceProtozoan ProteinsRNA Polymerase IVariant Surface Glycoproteins, Trypanosomaantigenic variationexpression site body (ESB)monoallelic exclusiontranscriptional regulationtrypanosomes

Identifiers

PMID41632842
PMCPMC12890818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.