ArticlePloS one2026
Spatial analysis of mortality due to congenital syphilis in Brazil from 2008 to 2022.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Congenital Syphilis in Brazil: Municipal Antenatal Care, Primary Health Care Capacity, and Territorial Inequalities, 2015-2024.Maternal and child health journal · 2026Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study is to analyze spatial distribution of mortality due to congenital syphilis in Brazil from 2008 to 2022. This is an ecological study that considered congenital syphilis deaths reported in all Brazilian municipalities, from 2008 to 2022, available in the Brazilian government's information systems. We built a thematic map to describe the distribution of congenital syphilis mortality in the country and, subsequently, applied the Local Index Spatial Analysis to identify possible spatial clusters. Finally, we used the Ordinary Least Squares and Geographically Weighted Regression models to identify mortality predictors in the territory. The mortality rate from congenital syphilis was 0.64 deaths per 1,000 live births. The distribution of deaths occurred heterogeneously, with the highest rates in the states of Pará, Acre, Rondônia, Rio de Janeiro and part of Amazonas. We identified statistically significant spatial clusters across the country, with the formation of clusters with a high-high pattern in Pará, Rio de Janeiro, and Mato Grosso (p < 0.05). We observed that the Gini index (p = 0.008; 95% Confidence Interval: 0.02-0.11), the number of nurses in primary care (p = 0.027; 95% Confidence Interval: 0.0005-0.00003) and the proportion of non-treponemal tests by pregnant women (p = 0.016; 95% Confidence Interval: 0.005-0.001) are variables that influence the occurrence of deaths. Congenital syphilis deaths in Brazil occur heterogeneously, with different rates between regions, which are geographically influenced by social and healthcare characteristics of the location.
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