Article in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Gal FinerDivision of Pediatric Nephrology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.ORCID 0000-0002-1488-9985
George S YacuDivision of Pediatric Nephrology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.
Mohammad Daud KhanDivision of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.ORCID 0009-0005-5476-2240
Yalu ZhouFeinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.
Gaurav GadhviDivision of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.ORCID 0000-0002-4379-2824
Sarah E WardDivision of Pediatric Nephrology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.
Mohammed SayedDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.ORCID 0000-0002-8004-2504
R Ariel GomezDepartment of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville, Virginia, United States.ORCID 0000-0002-5124-8255
Maria Luisa S Sequeira-LopezDepartment of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville, Virginia, United States.ORCID 0000-0002-4459-7940
Joo-Seop ParkFeinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.ORCID 0000-0002-4190-4386
Hee-Woong LimDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.ORCID 0000-0001-8599-1808
Susan E QuagginFeinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.ORCID 0000-0002-3706-5727
Deborah R WinterDivision of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.ORCID 0000-0003-1806-673X
Funding
Activation of the Angiopoietin-Tie2/TEK Pathway to Treat Ocular Hypertension and GlaucomaR01EY025799 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JIN, JING, QUAGGIN, SUSAN E. · 2016 to 2024
$5.8M
Resource Development CoreU54DK137516 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Eun Ji Paige Chung, Pinelopi P. Kapitsinou · 2023 to 2026
$4.8M
Macrophage Heterogeneity in Rheumatoid ArthritisR01AR080513 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Harris R Perlman, Deborah Rachelle Winter · 2022 to 2026
$3.3M
Synovial Macrophage Transcriptional Signatures for Predicting Therapeutic EfficacyR01AR075423 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERLMAN, HARRIS R · 2019 to 2023
$3.0M
Transcriptional Regulators in Aging MacrophagesR01AI163742 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WINTER, DEBORAH RACHELLE · 2021 to 2025
$3.0M
Functional Analysis of the Role of Transcription Factor 21 (Tcf21) in Nephron Progenitor Cells in Congenital Anomalies of the Kidney and Urinary TractK08DK118180 · NIDDK · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI FINER, GAL · 2020 to 2024
$814k
Investigating immunophenotypic and transcriptional heterogeneity as biomarkers of pain centralization in rheumatoid arthritisR21AR080351 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEE, YVONNE CLAIRE, WINTER, DEBORAH RACHELLE · 2022 to 2023
$387k
American Heart Association (AHA) 18CDA34110224American Thoracic Society (ATS)HHS | National Institutes of Health (NIH) R01AR075423HHS | National Institutes of Health (NIH) R01AR080513HHS | National Institutes of Health (NIH) R21AR080351HHS | NIH | National Eye Institute (NEI) R01EY025799-05HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) K08 DK118180-01A1HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) U54DK137516NEI NIH HHS R01 EY025799NIAID NIH HHS R01 AI163742NIAMS NIH HHS R01 AR080513NIAMS NIH HHS R21 AR080351NIDDK NIH HHS K08 DK118180NIDDK NIH HHS U54 DK137516
6 · The paper itself
Abstract
The stromal compartment of the developing kidney arises from forkhead box D1 (Foxd1)-expressing progenitors and gives rise to diverse cell types essential for nephrogenesis, including the renal stroma, capsule, mesangial cells, renin cells, pericytes, and vascular smooth muscle cells (VSMCs). However, the molecular mechanisms guiding their fate specification remain incompletely defined. Here, we identify the basic helix-loop-helix transcription factor Tcf21 as a critical determinant of stromal cell identity during kidney development. We performed single-cell RNA sequencing (scRNA-seq) on Foxd1-lineage cells isolated from embryonic
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The transcription factor Tcf21 is necessary for adoption of cell fates by · full record | OpenQuestion