ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2026
Dietitian-led very low-calorie diet for preoperative rehabilitation in patients with obesity awaiting non-bariatric elective laparoscopic surgery: A retrospective study.
Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundObesity increases the risks and complexity of laparoscopic surgeries. Preoperative very low-calorie diets (VLCDs) can demonstrate significant preoperative weight loss. However, the optimal VLCD duration remains unclear. Excessive loss of muscle mass associated with VLCDs may elevate surgical and postoperative risks. This study aimed to assess the impact of a dietitian-led preoperative VLCD intervention on changes in weight, muscle, and fat mass and to examine their relationships with intervention duration and surgical time.
methodsA retrospective chart review of patients attending a dietitian-led VLCD outpatient clinic for 1-8 weeks. Primary outcomes were changes in weight, muscle and fat mass, and their relationships with VLCD duration. Associations between preoperative fat mass and operative time for cholecystectomies and hernia repairs were explored using a general linear model.
resultsOne hundred fifty-seven participants (97 female; mean body mass index, 39.2) achieved significant weight reduction (6.4 kg, P < 0.001). Muscle mass accounted for 28.5% of mean weight loss and fat mass for 68%, with an increased muscle to fat ratio (P < 0.001). VLCDs of >4 weeks showed greater median muscle mass loss (26.9% vs 8.8%). Operative time decreased by an estimated 0.61 min for every kilogram reduction in preoperative fat mass, after adjusting for surgical type (P < 0.001, adjusted R
conclusionsA dietitian-led preoperative VLCD intervention for 5-8 weeks can achieve clinically significant weight loss, primarily from fat mass. Exploratory analysis suggested lower preoperative fat mass may contribute to shorter surgical time, but further research is needed to control for other factors, such as complexity and surgeon experience.
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