Evidence map›Paper›PMID 41632367›Full record

ArticleAIDS and behavior2026

Barriers and Facilitators of Access and Adherence to Antiretroviral Therapy Among Young People Living with HIV in Shinyanga Region, Tanzania.

Constantine Alex Ntanguligwa, Marta Tilli, Beatrice Borchi, Optat Kajuna, Angela Munishi, Christina Jahari, Chrispin Mgute, Idd Amiri Salehe, Marianne Strohmeyer, Valentina Petrini and 7 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Constantine Alex NtanguligwaDoctors with Africa CUAMM, Shinyanga, Tanzania.
Marta TilliDoctors with Africa CUAMM, Shinyanga, Tanzania.
Beatrice BorchiInfectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.
Optat KajunaDoctors with Africa CUAMM, Shinyanga, Tanzania.
Angela MunishiDoctors with Africa CUAMM, Shinyanga, Tanzania.
Christina JahariDoctors with Africa CUAMM, Shinyanga, Tanzania.
Chrispin MguteDoctors with Africa CUAMM, Shinyanga, Tanzania.
Idd Amiri SaleheDoctors with Africa CUAMM, Shinyanga, Tanzania.
Marianne StrohmeyerDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Valentina PetriniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Chiara DidonèDoctors with Africa CUAMM, Shinyanga, Tanzania.
Giovanni PutotoDoctors with Africa CUAMM, Padua, Italy.
Gaetano AzzimontiDoctors with Africa CUAMM, Padua, Italy.
Alessandro BartoloniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Lorenzo ZammarchiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy. lorenzo.zammarchi@unifi.it.
Giulia MorigoniTuscany Regional Health Agency, Florence, Italy.
Francesca IerardiTuscany Regional Health Agency, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advancements in antiretroviral therapy (ART) in Tanzania, adherence remains a challenge, especially among young people living with HIV (YPLHIV) aged 10-24 years. This study, conducted in the Shinyanga region of Tanzania, explored the factors affecting access and adherence to ART among YPLHIV. Access to ART refers to the ability to reach, enroll, and receive HIV care and education; adherence refers to proper use of medications as prescribed. The research employed focus group discussions and in-depth interviews with YPLHIV and their caregivers. Data were transcribed and thematically analyzed using Atlas.ti software. The qualitative data analysis revealed clear categories of barriers and facilitators. Barriers to ART access and adherence included forgetfulness, lack of privacy, family instability, poverty, reflected in lack of food or water. Perceived stigma and discrimination from family, school or community members played a significant role, alongside low participation in adherence support activities. Factors facilitating ART access and adherence included disclosure of HIV status and access to social or emotional support from the family members, peers, teachers, health workers, and community members. These factors may increase knowledge about the risks of treatment failure and drug resistance, help reduce their perceived stigma and discrimination and support treatment continuity. Interventions by health workers, family members, peers, teachers-at individual and social levels-as well as by government and local health authorities-at the policy level-are needed to address the above barriers and facilitators to ART access and adherence among YPLHIV enrolled in HIV care. A pesar de los avances en la terapia antirretroviral (TAR) en Tanzania, la adherencia sigue siendo un desafío, especialmente entre los jóvenes que viven con VIH (JVVHIV) de entre 10 y 24 años. Este estudio, realizado en la región de Shinyanga en Tanzania, exploró los factores que afectan el acceso y la adherencia a la TAR entre los JVVHIV. El acceso a la TAR se refiere a la capacidad de llegar, inscribirse y recibir atención y educación sobre el VIH; la adherencia se refiere al uso adecuado de los medicamentos según lo prescrito. La investigación empleó discusiones en grupos focales y entrevistas en profundidad con los JVVHIV y sus cuidadores. Los datos fueron transcritos y analizados temáticamente utilizando el software Atlas.ti. El análisis cualitativo reveló categorías claras de barreras y facilitadores. Las barreras al acceso y la adherencia a la TAR incluyeron el olvido, la falta de privacidad, la inestabilidad familiar y la pobreza, reflejada en la falta de alimentos o agua. La percepción de estigma y discriminación por parte de familiares, compañeros de escuela o miembros de la comunidad desempeñó un papel significativo, junto con una baja participación en actividades de apoyo a la adherencia. Los factores que facilitan el acceso y la adherencia a la TAR incluyeron la divulgación del estado serológico y el acceso a apoyo social o emocional por parte de familiares, compañeros, maestros, trabajadores de la salud y miembros de la comunidad. Estos factores pueden aumentar el conocimiento sobre los riesgos de fracaso del tratamiento y resistencia a los medicamentos, ayudar a reducir la percepción de estigma y discriminación y apoyar la continuidad del tratamiento. Se necesitan intervenciones por parte de los trabajadores de la salud, familiares, compañeros, maestros-a nivel individual y social-así como por parte del gobierno y las autoridades sanitarias locales-a nivel de políticas-para abordar las barreras y facilitadores mencionados en el acceso y adherencia a la TAR entre los JVVHIV inscritos en cuidados por VIH.

Indexed as

Anti-HIV AgentsAnti-Retroviral AgentsHealth Services AccessibilityHIV InfectionsMedication AdherenceAdherence InterventionsAdolescentChildFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMaleQualitative ResearchSocial StigmaAnti-HIV AgentsAnti-Retroviral AgentsAccess to HIV servicesAdherence to ARTAdolescents and young adults living with HIVBarriersFacilitatorsTanzania

Identifiers

PMID41632367
PMCPMC13486090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.