Evidence map›Paper›PMID 41631995›Full record

ArticleInternational journal of surgery (London, England)2026

Ultrasound-guided thyroid cartilage plane block for superior laryngeal nerve blockade in awake fiberoptic tracheal intubation: combined cadaveric validation and randomized clinical trial.

Tao Shan, Mufeng Gu, Xiao Zhou, Ying Ji, Hongguang Bao, Hongwei Shi, Jie Wei, Qilian Tan, Liu Han, Lihai Chen

Abstract read
In one paragraph

Article in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tao ShanDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.ORCID 0000-0002-4933-0460
Mufeng GuDepartment of Human Anatomy, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China.
Xiao ZhouDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.ORCID 0009-0000-1166-7183
Ying JiDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Hongguang BaoDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Hongwei ShiDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Jie WeiDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Qilian TanDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Liu HanDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.ORCID 0000-0003-2993-0394
Lihai ChenDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe thyroid cartilage plane (TCP) block is a novel approach for superior laryngeal nerve (SLN) block in awake tracheal intubation (ATI). We aimed to evaluate the efficacy and safety of TCP block for ATI. MATERIALS AND

methodsOur study included a cadaver dissection and a clinical study. Detailed anatomical dissections were performed on two fresh cadavers after a bilateral TCP block with methylene blue. Sixty patients scheduled for ATI were randomized to receive either bilateral TCP block (TCP group) or fiberoptic bronchoscope-assisted topical anesthesia (FIB group) to anesthetize the vocal cords. A 22-gauge needle was advanced targeting the thyroid cartilage laminae, followed by injection of 2.5 ml lidocaine in the TCP group. Lidocaine spray was applied to anesthetize the remainder of the airway. The primary outcome was quality of airway anesthesia grade during intubation (0, excellent; 1, good; 2, fair; 3, poor; 4, very poor), with secondary outcomes including hemodynamic profile, Ramsay sedation score, and incidence of airway hemorrhage and SLN injury.

resultsThe methylene blue stained all the internal branches of SLN, with one external branch not stained. In the clinical study, the quality of airway anesthesia was significantly better in the TCP group than in the FIB group (median [IQR], 0 [0-0] vs 1 [0-2], difference [95% CI]: 1 [0-1], P < 0.001). Mean arterial pressure and HR were better maintained during intubation in the TCP group (P < 0.05). Neither airway hemorrhage nor nerve injury was observed.

conclusionUltrasound-guided TCP block is an effective and safe approach for the SLN blockade, providing an alternative for ATI.

Indexed as

awake tracheal intubationnerve blockregional anesthesiasuperior laryngeal nervethyroid cartilage planeultrasonography

Identifiers

PMID41631995
PMCPMC13105536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.