Evidence map›Paper›PMID 41631974›Full record

ArticleEmerging microbes & infections2026

Assembling the puzzle of antimicrobial resistance in staphylococcal biofilms.

Thuy Nguyen, David McGiffin, Bin Lou, Yao Sun, Changrui Qian, Xenia Kostoulias, Wenhong Zhang, Anton Y Peleg, Yue Qu

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Photoinactivation ofRSC advances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thuy NguyenInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
David McGiffinDepartment of Cardiothoracic Surgery, The Alfred and Monash University, Melbourne, Australia.
Bin LouInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Yao SunInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Changrui QianInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Xenia KostouliasInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Wenhong ZhangDepartment of Infectious Diseases, National Centre for Infectious Diseases of China, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Anton Y PelegInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Yue QuInfection Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple mechanisms underpinning biofilm antimicrobial resistance (AMR) have been studied individually. This study aimed to integrate these mechanisms, to understand their contributions to staphylococcal biofilm AMR, as a part of a whole, and to elucidate key hurdles hindering effective biofilm eradication by antimicrobial agents. Nine antibiotics were selected against microplate-based biofilms formed by

Indexed as

Anti-Bacterial AgentsBiofilmsDrug Resistance, BacterialStaphylococcus aureusStaphylococcus epidermidisExtracellular Polymeric Substance MatrixHydrogen-Ion ConcentrationMicrobial Sensitivity TestsStaphylococcal InfectionsAnti-Bacterial Agentsacidic pHantimicrobial resistance (AMR)biofilm killinginoculum effectslow-cell metabolismpenetrationStaphylococcal biofilms

Identifiers

PMID41631974
PMCPMC12903938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.