Evidence map›Paper›PMID 41631760›Full record

ArticleJournal of the American Heart Association2026

Intermediate Conductance Calcium-Activated Potassium Channel Activation in Stem Cell Antigen-1 Positive Cells Contributed to Vascular Restenosis.

Yiting Liu, Xinyi Zeng, Min Zhang, Xiangdong Yang, Chunshu Li, Hai Tian, Mengying Zhu, Pengyun Li, Jun Cheng, Qingbo Xu and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yiting Liu *Key Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0006-5248-3157
Xinyi Zeng *Key Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0001-9241-9161
Min Zhang *Key Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0003-8471-7710
Xiangdong Yang *Experimental Medicine Centre The Affiliated Hospital of Southwest Medical University Luzhou China.
Chunshu LiKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0004-3030-5224
Hai TianKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0008-2386-5054
Mengying ZhuKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0008-7934-1962
Pengyun LiKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0001-4551-2224
Jun ChengKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0009-0006-1001-0941
Qingbo XuKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0000-0003-2474-8155
Yan YangKey Lab of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Lab of Sichuan Province, Collaborative Innovation Centre for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Luzhou China.ORCID 0000-0003-3029-8293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular restenosis, a common complication following vascular reconstruction, results in stenosis or blockage that impairs vascular remodeling. This process is driven by the activation of vascular stem cells. Growing evidence suggests that intermediate conductance calcium-activated potassium (IK

methodsTo investigate the role and mechanism of the IK

resultsGenetic deletion of IK

conclusionsThis study clarifies the role of the IK

Indexed as

Antigens, LyFemoral ArteryGraft Occlusion, VascularIntermediate-Conductance Calcium-Activated Potassium ChannelsStem CellsAnimalsCell ProliferationCells, CulturedDisease Models, AnimalMaleMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutNeointimap38 Mitogen-Activated Protein KinasesAntigens, LyIntermediate-Conductance Calcium-Activated Potassium ChannelsKcnn4 protein, mouseLy6a protein, mouseMembrane Proteinsp38 Mitogen-Activated Protein KinasesIKCa channelmigrationproliferationSca‐1+ cellsvascular restenosis

Identifiers

PMID41631760
PMCPMC13055779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.