Evidence map›Paper›PMID 41631745›Full record

ArticleJournal of the American Heart Association2026

Assessing Potential Benefit of Stroke Prophylaxis Therapy in Atrial Fibrillation and Atrial Flutter Using a Novel Competing Risk Scoring Tool.

Anthony J Mazzella, Thomas C Daubert, Wanting Jin, Quefeng Li, Lindsey Rosman, Anil K Gehi

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anthony J MazzellaDivision of Cardiology, Department of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.ORCID 0000-0003-2036-9254
Thomas C DaubertDivision of Cardiology, Department of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.ORCID 0009-0000-2587-8264
Wanting JinDepartment of Biostatistics University of North Carolina Gillings School of Global Public Health Chapel Hill NC USA.ORCID 0000-0002-3258-8828
Quefeng LiDepartment of Biostatistics University of North Carolina Gillings School of Global Public Health Chapel Hill NC USA.ORCID 0000-0003-0707-2763
Lindsey RosmanDivision of Cardiology, Department of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.ORCID 0000-0002-0944-6864
Anil K GehiDivision of Cardiology, Department of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.ORCID 0000-0002-6724-5294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe competing risk of nonstroke mortality may limit the potential benefit of stroke prophylaxis therapy in patients with atrial fibrillation or atrial flutter AF.

methodsUsing a Medicare 20% sample, we identified a cohort of beneficiaries diagnosed with atrial fibrillation or atrial flutter from 2006 to 2019 using

resultsAmong a total of 1 883 759 Medicare beneficiaries, 330 136 patients were included with median age of 79.7 years. 54% of patients had prior bleeding episodes. The median CHA

conclusionsWe propose a scoring tool to identify the potential benefit of thromboembolic prophylaxis therapy in older patients diagnosed with atrial fibrillation or atrial flutter. This tool can be used in shared decision-making settings. Further studies to improve and validate this scoring tool are warranted.

Indexed as

AnticoagulantsAtrial FibrillationAtrial FlutterStrokeAgedAged, 80 and overFemaleHumansMaleMedicareRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesAnticoagulantsanticoagulationatrial fibrillationcompeting riskmortalitythromboembolic prophylaxis

Identifiers

PMID41631745
PMCPMC13055728

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.