ArticleJournal of the science of food and agriculture2026
Essential and toxic elements intake from botanical extracts: a probabilistic risk-benefit evaluation within the Italian dietary context.
Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBotanical extracts are widely consumed for their claimed health benefits, yet their safety profile with respect to chronic consumption remains poorly characterized. Understanding the potential health risks associated with their inorganic content is a crucial issue for ensuring safe use, along with a characterization of the concurrent nutritional contribution of the mineral component.
resultsThe present study aimed to quantitatively assess exposure levels and potential health impacts of chronic intake of ten essential (Ca, K, P, Fe, Mg and Zn) and potentially toxic (Al, As, Ni and Pb) elements through the consumption of botanical extracts (n = 25) among Italian adults. A probabilistic approach was employed to estimate exposure levels and both risk and benefit metrics. Results indicated that botanicals alone contributed only minimally to mineral intakes, with 5
conclusionThe findings of the present study underscore the importance of the cautious dietary use of botanical extracts because of potential risks that may outweigh the presumed benefits. © 2026 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
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