An internet-based cognitive-behavioral self-management intervention for patients with hand osteoarthritis or fibromyalgia - Two randomized controlled trials.

Jessy A Terpstra, Sylvia van Beugen, Rosalie van der Vaart, Roxy A van Eersel, Elise Dusseldorp, Margreet Kloppenburg, Andrea W M Evers

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Article in Internet interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jessy A TerpstraHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Sylvia van BeugenHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Rosalie van der VaartHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Roxy A van EerselHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Elise DusseldorpHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Margreet KloppenburgDepartment of Rheumatology, Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands.

Andrea W M EversHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, PO Box 9555, 2300 RB, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rheumatic and musculoskeletal diseases have a high burden. We aimed to evaluate the effectiveness of a therapist-guided internet-based cognitive-behavioral therapy (iCBT) on pain coping and secondary physical, psychological, and disease impact outcomes in hand osteoarthritis and fibromyalgia. Method: Two single-center, parallel-group, superiority randomized controlled trials were performed. In one study, 70 adults with hand osteoarthritis visiting a Dutch hospital were randomized to care-as-usual or care-as-usual plus iCBT (each group Results: In patients with hand osteoarthritis (mean age = 62.4 ± 7.6), no between-group effect on pain coping was found at post-intervention ( Conclusions: ICBT improved pain coping in fibromyalgia at the primary endpoint, whereas the hand osteoarthritis trial was negative at the primary endpoint. Exploratory secondary findings suggest potential benefits for both conditions but warrant replication, particularly in subgroups with a high disease impact.

Indexed as

Chronic painCognitive behavioral therapyFibromyalgiaHand osteoarthritisRheumatic diseasesSelf-management

Identifiers

PMID41631249

DOI10.1016/j.invent.2026.100908

PMCPMC12861268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.