Evidence map›Paper›PMID 41631191›Full record

ReviewSynthetic and systems biotechnology2026

Sustainable production of glutaric acid in microbial cell factories: Current advances and future prospects.

Jie Liu, Dan Mei, Xuan-Jun Zhang, Wei-Guo Zhang, Long-Bao Zhu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie LiuSchool of Biological and Food Engineering, Anhui Polytechnic University, 18Beijing Middle Road, WuHu, 241000, People's Republic of China.
Dan MeiSchool of Biological and Food Engineering, Anhui Polytechnic University, 18Beijing Middle Road, WuHu, 241000, People's Republic of China.
Xuan-Jun ZhangSchool of Biological and Food Engineering, Anhui Polytechnic University, 18Beijing Middle Road, WuHu, 241000, People's Republic of China.
Wei-Guo ZhangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, WuXi, 214122, People's Republic of China.
Long-Bao ZhuSchool of Biological and Food Engineering, Anhui Polytechnic University, 18Beijing Middle Road, WuHu, 241000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutaric acid is a significant C5 dicarboxylic acid, extensively utilized in the chemical industry, medicine, and biomaterials. In recent years, the advancement of synthetic biology and metabolic engineering has rendered microbial production of glutaric acid a sustainable alternative to conventional chemical synthesis. This study reviews recent advancements in glutaric acid biosynthesis, primarily concentrating on the design of biosynthetic pathways and metabolic engineering strategies for the development of engineered strains. The utilization of systems biology technologies in the development of the glutaric acid biosynthetic pathway is examined. This study outlines the issues associated with glutaric acid biosynthesis and its prospective developmental trajectory, intending to offer theoretical insights and technological guidance for the sustainable production of glutaric acid and related fine chemicals.

Indexed as

Glutaric acidGreen manufacturingMetabolic engineeringMicrobial cell factoriesSustainable production

Identifiers

PMID41631191
PMCPMC12861294

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.