Evidence map›Paper›PMID 41630990›Full record

ArticleMolecular therapy. Nucleic acids2026

Improving angiogenesis ameliorates the efficacy of ASO-based exon skipping for the treatment of Duchenne muscular dystrophy.

Mathilde Blitek, Cécile Gastaldi, Mathilde Doisy, Olivier Le Coz, Marion David, Xaysongkhame Phongsavanh, Sameh Ben Aicha, Luis Garcia, Alessio Rotini, Gilles Pagès and 1 more

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mathilde BlitekUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Cécile GastaldiMedical Biology Department, Centre Scientifique de Monaco, Monaco 98000, Principality of Monaco.
Mathilde DoisyUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Olivier Le CozUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Marion DavidKekkan Biologics, Strasbourg, France.
Xaysongkhame PhongsavanhUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Sameh Ben AichaInstitute of Biology Valrose, University Cote d'Azur, CNRS, Inserm, Nice, France.
Luis GarciaUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Alessio RotiniUniversity Paris Est Creteil, INSERM, IMRB, 94010 Creteil, France.
Gilles PagèsUniversity Côte d'Azur, Institute for Research on Cancer and Ageing of Nice (IRCAN), UMR CNRS 7284/U INSERM 1081, Nice, France.
Aurélie GoyenvalleUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a severe X-linked disease caused by pathogenic variants in the

Indexed as

angiogenesiscombined therapyDuchenne muscular dystrophyexon skippingLVRFmicrovasculatureMT: Oligonucleotides: Therapies and Applicationssplice switching

Identifiers

PMID41630990
PMCPMC12860987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.