Evidence map›Paper›PMID 41630883›Full record

ArticleFood chemistry: X2026

Screening and identification of novel anti-inflammatory peptides from sea cucumber gonads: In silico and in vitro analysis.

Zhiqin Zhang, Yongke Deng, Jingxuan Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Haimei Liu, Qin Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiqin ZhangCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.
Yongke DengCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.
Jingxuan WangCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.
Peipei DouDepartment of Animal and Food Sciences, University of Kentucky, Lexington, KY, 40546, USA.
Hongbing FanDepartment of Animal and Food Sciences, University of Kentucky, Lexington, KY, 40546, USA.
Xiangquan ZengDepartment of Food Science, College of Agriculture, Purdue University, West Lafayette, IN, United States.
Xinguang FanCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.
Haimei LiuCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.
Qin ZhaoCollege of Food Engineering, Ludong University, Yantai, Shandong 264025, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study identified three novel anti-inflammatory peptides from sea cucumber gonad hydrolysates: GDRGF, FDGPEGPRGPPGSEGRQG, and PSNLGTGLR. In vitro experiments demonstrated that these peptides, at concentrations ranging from 25 to 400 μg/mL, exhibited no cytotoxicity toward RAW264.7 macrophages and significantly promoted cell proliferation (

Indexed as

Anti-inflammatory peptidesLipopolysaccharideMolecular dockingPro-inflammatory cytokinesSea cucumber gonad

Identifiers

PMID41630883
PMCPMC12861254

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.