ArticleJAAD international2026
Prevalence, multiterritorial vascular distribution, and burden of subclinical atherosclerosis in psoriasis: The EDSAP study.
Article in JAAD international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Psoriasis increases atherosclerosis risk due to inflammation. To date, subclinical atherosclerosis (SA) in psoriasis has only been studied in individual vascular territories by imaging. Objective: To conduct a comprehensive evaluation of multiterritorial SA prevalence in psoriasis by imaging and establish its relationships with cardiovascular (CV) risk scores. Methods: A total of 120 patients with moderate-to-severe psoriasis without CV disease from the Early Detection of Subclinical Atherosclerosis in Psoriasis (EDSAP) cohort underwent vascular ultrasound of carotid/femoral arteries and noncontrast/contrast-coronary computed tomography angiography. SA was defined by the presence of any plaque or a coronary artery calcium score ≥1. Results: The median age was 48.04 (8.25) years, 73% were male, and 77% of participants had SA. Femoral arteries were most affected (57.1%), followed by the coronaries (51.3%) and carotid arteries (49.6%). Femoral plaques exhibited the strongest associations with coronary parameters. CV risk scores underestimated SA, as at least 60% low-risk and 90% moderate-risk patients had SA. Limitations: The main limitation is the small sample size. Conclusions: This study provides the first multiterritorial assessment of SA in psoriasis, revealing a high prevalence of early disease. Femoral arteries were most affected, correlating with coronary atherosclerosis. The high SA detection within low-/intermediate-risk individuals suggests recalibrating CV scores for establishing effective preventive measures.
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