Observational studyDevelopmental medicine and child neurology2026
Early neurodevelopmental outcome in newborns with mild hypoxic-ischaemic encephalopathy.
Observational study in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Early neurodevelopmental outcome in newborns with mild hypoxic-ischaemic encephalopathy.Developmental medicine and child neurology · 2026Observational
- Redefining mild hypoxic-ischaemic encephalopathy: A fundamental step to therapeutic progress.Developmental medicine and child neurology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
aimTo describe the natural history of newborn children with mild hypoxic-ischaemic encephalopathy in the first year of life.
methodThis was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian Society of Neonatology guidelines. To make the clinical evaluation homogeneous at each centre, a training neurological courses was provided to all operators involved in the study. Forty newborn children (23 males and 17 females) underwent neonatal and infant neurological examination (Hammersmith Neonatal Neurological Examination and Hammersmith Infant Neurological Examination), brain magnetic resonance at 7 to 10 days, electroencephalogram between 6 months and 12 months, and Griffiths Scales of Child Development, Third Edition to assess neurodevelopmental outcome at 12 months.
resultsAll of these infants demonstrated typical neuromotor development and age-appropriate developmental quotients at 12 months, even in the few showing abnormalities at magnetic resonance imaging assessment or neurological assessment during the neonatal period.
interpretationCurrent classifications of mild hypoxic-ischaemic encephalopathy may misclassify risk, highlighting the need for refined diagnostic criteria and early staging tools that can be used within the first 6 hours of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.