Evidence map›Paper›PMID 41630512›Full record

ArticleClinical psychology & psychotherapy

Goal Pursuit-Focused CBT for Bipolar Disorder: A Four-Case Series.

Andrea Gragnani, Allison Uvelli, Marco Saettoni

Abstract readCase Reports
In one paragraph

Article in Clinical psychology & psychotherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea GragnaniSchool of Cognitive Psychotherapy (SPC), Grosseto, Italy.ORCID https://orcid.org/0000-0001-9129-8794
Allison UvelliSchool of Cognitive Psychotherapy (SPC), Grosseto, Italy.ORCID https://orcid.org/0000-0002-1050-3133
Marco SaettoniSchool of Cognitive Psychotherapy (SPC), Grosseto, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBD is a chronic, cyclical condition marked by severe mood instability and significant impairment. Although pharmacological and psychotherapeutic interventions have demonstrated efficacy, challenges remain in preventing relapse and sustaining long-term euthymia. This study evaluates a CBT-based intervention designed to reduce symptom severity and recurrence by targeting three core maintenance factors: intolerance of anergic states, addiction to mania, and meta-emotional problems.

methodFour individuals diagnosed with BD participated in a one-year CBT intervention tailored to address these key vulnerabilities. Assessments were conducted at baseline, post-treatment, and at 18- and 24-month follow-ups, measuring depression, mania, quality of life, and personality functioning. Changes were evaluated with RCI and repeated measures ANOVA.

resultsAll four patients showed a marked reduction in depressive symptoms at the end of treatment and at the 24-month follow-up, with a large effect size (η

conclusionDespite limitations, these preliminary findings suggest that this three-goal CBT intervention targeting core maintenance factors in bipolar disorder may promote sustained clinical improvements, increase long-term stability, and reduce reliance on medication.

Indexed as

Bipolar DisorderCognitive Behavioral TherapyGoalsAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedQuality of LifeTreatment Outcomebipolar disordercase seriescognitive behavioural therapyeuthymia maintenancetreatment adherence

Identifiers

PMID41630512
PMCPMC12865336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.