ArticleGerodontology2026
Potential Applications of Nano Silver Fluoride in the Prevention of Dental Caries in Older Adults: A Scoping Review.
Article in Gerodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental caries remains highly prevalent in older adults and represents a growing public health concern due to increased tooth retention, polypharmacy, hyposalivation and functional limitations. Silver diamine fluoride (SDF) is widely used for caries arrest in this population but causes undesirable tooth staining. Nano Silver Fluoride (NSF) has emerged as a potential alternative, combining antimicrobial and remineralizing properties with improved aesthetics. However, its applicability in geriatric dentistry remains unclear.
objectiveThis scoping review aimed to identify and map existing evidence on the use of Nano Silver Fluoride for the prevention or management of dental caries in older adults.
methodsThe review followed the PRISMA-ScR guidelines framework. A systematic search was conducted in PubMed, Scopus, Web of Science, Cochrane Library, and SciELO for articles published between January 2020 and December 2024. Studies were eligible if they involved human participants aged ≥ 60 years, evaluated NSF for caries prevention or treatment and were published in English, Spanish or Portuguese. In vitro studies, animal models, case reports, reviews, and studies on children or young adults only were excluded.
resultsA total of 157 records were identified; 14 full-text articles were assessed. None met the inclusion criteria, as all clinical studies involving NSF were conducted in paediatric or young adult populations, lacked older adult participants, or were laboratory-based. No clinical trials, observational studies, or reviews evaluating NSF in older adults were found. DISCUSSION: This scoping review reveals a complete absence of clinical evidence regarding the use of Nano Silver Fluoride in adults aged 60 years or older. Although NSF has shown promising results in younger populations and is chemically related to SDF, its effectiveness and safety in geriatric dentistry remain unknown. High-quality clinical studies in older adults are urgently needed.
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