Evidence map›Paper›PMID 41630475›Full record

ArticleTurkish journal of surgery2026

Total mesorectal excision quality as a predictor of overall survival in rectal cancer: A retrospective cohort study.

Alisina Bulut, Muhammed İkbal Akın, Barış Dağdemir, Ahmet Ufuk Caniklioğlu, Mehmet Fatih Tekin, Leyla Semiha Şen, Wafi Attaallah

Abstract read
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Article in Turkish journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Alisina BulutDepartment of General Surgery, Marmara University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0003-3849-3333
Muhammed İkbal AkınDepartment of Gastrointestinal Surgery, University of Health Sciences Türkiye, Koşuyolu High Specialization Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-9638-4031
Barış DağdemirDepartment of General Surgery, Marmara University Faculty of Medicine, İstanbul, Türkiye.ORCID 0009-0007-7967-7709
Ahmet Ufuk CaniklioğluDepartment of General Surgery, Marmara University Faculty of Medicine, İstanbul, Türkiye.ORCID 0009-0007-5074-6731
Mehmet Fatih TekinDepartment of Pathology, Maramara University Pendik Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-3998-2860
Leyla Semiha ŞenDepartment of General Surgery, Maramara University Pendik Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0003-3006-2061
Wafi AttaallahClinic of General Surgery, Anadolu Medical Center in affiliation with Johns Hopkins Medicine, Kocaeli, Türkiye.ORCID 0000-0002-3179-4144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Achieving complete total mesorectal excision (TME) is considered an important indicator of surgical quality in rectal cancer surgery. However, the impact of TME quality on overall survival (OS) remains controversial. This study aimed to evaluate the association between TME quality and OS in patients undergoing rectal cancer surgery. Material and Methods: A retrospective analysis was conducted on 171 patients who underwent elective low anterior resection or abdominoperineal resection for rectal cancer between 2021 and 2022. OS was compared between patients with incomplete TME and those with near-complete or complete TME. In addition, clinical and pathological factors associated with TME quality were assessed. Results: Incomplete TME was independently associated with worse OS [hazard ratio (HR)=2.53, 95% confidence interval (CI) 1.15-5.59, p=0.021], while undergoing a Hartmann procedure showed the strongest negative impact on OS (HR=4.60, 95% CI 2.04-10.38, p<0.001). At 36 months, OS was 86.3% in the near-complete/complete TME group versus 68.3% in the incomplete group (log-rank p=0.008). Factors associated with incomplete TME included lower preoperative albumin levels, larger tumor size, previous abdominal surgery, tumors located closer to the anal verge, lymphovascular invasion, and positive circumferential resection margins. Conclusion: Incomplete TME was associated with significantly worse OS in patients undergoing rectal cancer surgery. These findings highlight the importance of achieving optimal TME quality. Larger prospective studies are warranted to validate these results.

Indexed as

mesorectal gradeoverall survivalRectal cancertotal mesorectal excision quality

Identifiers

PMID41630475
PMCPMC12964080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.