Evidence map›Paper›PMID 41630182›Full record

ArticleACS chemical neuroscience2026

4-Chlorobenzylamine Containing Maleic Acid Derivatives: Synthesis,

Muhammad Junaid Tariq, Madiha Kanwal, Athar Ata, Humaira Nadeem, Mahwish Siddiqui

Abstract read
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In one paragraph

Article in ACS chemical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Junaid TariqDepartment of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad 44000, Pakistan.
Madiha KanwalDepartment of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad 44000, Pakistan.ORCID 0000-0003-4915-6842
Athar AtaDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931-1295, United States.
Humaira NadeemDepartment of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad 44000, Pakistan.ORCID 0000-0002-0169-0811
Mahwish SiddiquiCapital University of Science and Technology, Islamabad 44000, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One way to protect neurons is to protect them from oxidative damage by reducing lipid peroxidation (LPO). Therapeutic medicines that target the inflammatory response have antioxidant activities and can also block inflammatory cascade pathways and counteract cell lyses. The goal of this investigation was to see if new maleic acid derivatives could protect the brain from scopolamine-induced amnesia. To evaluate and characterize the maleic acid derivatives, spectroscopic techniques such as

Indexed as

Alzheimer DiseaseAntioxidantsBenzylaminesMaleatesNeuroprotective AgentsAnimalsCholinesterase InhibitorsCyclooxygenase 2Lipid PeroxidationMaleMaze LearningMolecular Docking SimulationNF-kappa BOxidative StressRatsRats, WistarAntioxidantsBenzylaminesCholinesterase InhibitorsCyclooxygenase 2Maleatesmaleic acidNeuroprotective AgentsNF-kappa BScopolamineACE assayAlzheimerdockingDPPH assayH&EIHCmaleic acid derivatives

Identifiers

PMID41630182
PMCPMC12921690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.