ArticleWorld journal of surgical oncology2026
Psychological crisis in patients with primary liver cancer after transarterial chemoembolization: epidemiological characteristics and associated factors.
Article in World journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
backgroundTransarterial chemoembolization (TACE) remains a widely embraced therapeutic modality for primary liver cancer. The present study sought to explore the prevalence of psychological crisis in patients with primary liver cancer following TACE and pinpoint its associated factors, to provide actionable implications for enhancing clinical treatment and care protocols.
methodsA cross-sectional study design was utilized. Eligible participants were patients diagnosed with primary liver cancer who had undergone TACE and admitted to our hospital during the period from January 2023 to March 2025. The Triage Assessment Form (TAF) was adopted to assess the psychological crisis status of all enrolled patients.
resultsA total of 276 primary liver cancer patients who had received TACE were included in the final analysis. The mean total score of psychological crisis among these patients was 18.25 ± 3.17. Spearman rank correlation analysis revealed significant associations between psychological crisis scores and age, gender, marital status, educational level, and average monthly household income (all p < 0.05). Multivariate linear regression analysis, adjusted for clinical covariates (Child-Pugh class, BCLC stage, TACE session frequency, post-procedural pain, and complications), confirmed the above five sociodemographic factors as independent correlates of psychological crisis scores (all p < 0.05). Collectively, these factors explained 56.2% of the variance in the outcome variable, with no statistically significant associations observed between psychological crisis scores and the included clinical variables (all p > 0.05).
conclusionPatients with primary liver cancer following TACE exhibit moderate acute post-procedural psychological crisis-like states, which are primarily associated with sociodemographic vulnerability factors rather than objective clinical indicators. Targeted psychological screening and brief interventions for high-risk groups (younger patients, females, unmarried/divorced individuals, those with lower educational attainment, and lower household income) are critical to mitigate the adverse impacts of acute psychological distress on perioperative TACE care.
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