ArticleBMC infectious diseases2026
Self-management and sputum conversion in pulmonary tuberculosis: a prospective study.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 authors.
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Abstract
backgroundThis study aims to investigate the impact of patient self-management assessed through the self-management in tuberculosis patients (SMSTP) scale on the outcomes of intensive-phase antituberculosis treatment in newly diagnosed tuberculosis patients. Additionally, we explored the correlation between self-management and the risk of a sputum smear not converting to negative after 2 months of treatment and constructed a regression prediction model for predictive analysis.
methodsA prospective cohort study was conducted that strictly adhered to the inclusion and exclusion criteria. Baseline data were collected from 61 eligible participants, 59 of whom completed follow-up during the intensive phase and were ultimately included in the analysis. Logistic regression was employed to analyze the association between self-management status and sputum smear nonconversion after intensive-phase treatment. A predictive model was constructed to evaluate the prognostic value of self-management for smear nonconversion.
resultsThe sputum smear conversion rate after intensive-phase antituberculosis treatment was 76.3%. The total self-management ability score was 66.03 ± 8.55 points, and it was identified as a predictive factor for smear nonconversion (OR = 0.917, 95% CI: 0.847-0.992).
conclusionsThe total self-management ability score is associated with sputum smear conversion following intensive-phase antituberculosis treatment. Targeted interventions to improve self-management may enhance treatment outcomes in patients.
trial registrationChinese Clinical Trial Registry, ChiCTR2500096661. Registered 27 January 2025; Retrospectively registered.
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