Trial reportJournal of general internal medicine2026
Champion-Led Deprescribing for Persons with Dementia in Primary Care: A Qualitative Study in Accountable Care Organizations.
Trial report in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05359679 (Impact Collaboratory Transforming Dementia Care - Can Value Champions Reduce Inappropriate Prescribing for People With Dementia?), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact Collaboratory Transforming Dementia Care - Can Value Champions Reduce Inappropriate Prescribing for People With Dementia?
Who cites it
1 citing paper in PubMed.
- A qualitative analysis to identify implementation strategies for a deprescribing clinical practice guideline using the CFIR-ERIC Matching Tool: perspectives from consumers and professional stakeholders.International journal of clinical pharmacy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundClinical champions are a known strategy for implementing evidence-based practices; however, their application in de-implementing potentially inappropriate medications (PIMs) among persons with dementia is underexplored. We conducted a pragmatic cluster-randomized clinical trial of a champion-led deprescribing intervention in accountable care organization (ACO) primary care settings.
objectiveTo (1) understand clinical champions' perspectives of their deprescribing projects and (2) identify key contextual factors that influenced champions' deprescribing PIMs for persons with dementia within ACO primary care.
designA qualitative study guided by the de-implementation outcomes framework.
participantsClinician champions who engaged in deprescribing projects. APPROACH: Data sources included transcripts from monthly learning calls and semi-structured interviews. All champions were invited to participate in learning calls and semi-structured interviews. The 30- to 60-min interviews were conducted using a semi-structured guide. We coded transcripts and performed thematic analysis to identify overarching themes. KEY
resultsEleven champions participated. Feasibility and fidelity of deprescribing were commonly undermined by external and organizational disruptions. Five contextual factors influenced champions' experiences: limited organizational readiness, lack of information technology infrastructure to support data access and patient identification, the importance of relationship-building and care coordination, the dyadic nature of deprescribing involving care partners, and the pharmacist's role as a multidisciplinary liaison. Champions employed adaptive, communication- and relationship-centered strategies to support deprescribing efforts.
conclusionsChampion-led deprescribing for persons with dementia is shaped by key contextual factors within ACO primary care settings. Dementia-specific training helped clinicians tailor deprescribing to local needs, but sustained efforts require supportive organizational structures, including ongoing education, accessible clinical data, and multidisciplinary collaboration. Primary care clinicians are uniquely positioned to lead personalized deprescribing conversations while pharmacists serve as liaisons with providers, patients, and care partners to coordinate deprescribing. Interventions that align with value-based care principles may strengthen system-level coordination and promote safer medication management in dementia care.
trial registrationClinicalTrials.gov ID: NCT05359679.
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