Evidence map›Paper›PMID 41629438›Full record

ArticleScientific reports2026

Cardiovascular risk assessed using the SCORE system and blood renalase concentration in the Polish subpopulation of the PURE study.

Aleksandra Żórawik, Wojciech Hajdusianek, Katarzyna Połtyn-Zaradna, Agnieszka Kusnerz, Rafał Poręba, Andrzej Szuba, Paweł Gać, Katarzyna Zatońska

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksandra ŻórawikDepartment of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, Wroclaw, 50- 368, Poland.
Wojciech HajdusianekDepartment of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, Wroclaw, 50- 368, Poland.
Katarzyna Połtyn-ZaradnaDepartment of Population Research and Prevention of Civilization Diseases, Wroclaw Medical University, Bujwida 44, Wroclaw, 50-372, Poland.
Agnieszka KusnerzDepartment of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, Wroclaw, 50- 368, Poland.
Rafał PorębaDepartment of Biological Principles of Physical Activity, Wroclaw University of Health and Sport Sciences, Paderewskiego 35, Wroclaw, 51-612, Poland.
Andrzej SzubaDepartment of Angiology and Internal Diseases, Wroclaw Medical University, Borowska 213, Wroclaw, 50-556, Poland.
Paweł GaćDepartment of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, Wroclaw, 50- 368, Poland. pawelgac@interia.pl.
Katarzyna ZatońskaDepartment of Population Research and Prevention of Civilization Diseases, Wroclaw Medical University, Bujwida 44, Wroclaw, 50-372, Poland.

Funding

Wroclaw Medical University SUBZ.E264.23.039 and SUBZ.E260.24.047
6 · The paper itself

Abstract

Prospective Urban and Rural Epidemiology (PURE) study is an international cohort study. Cardiovascular diseases (CVD) are a leading cause of death among worldwide. Several scales were developed to assess cardiovascular risk – one of them is SCORE system. Renalase is chemical compound which association with cardiovascular risk is likely but yet uncertain. The aim of this study was to assess the association between cardiovascular risk assessed using the SCORE system and blood renalase concentration in the Polish subpopulation of PURE study. The study group was composed of 269 participants (156 female and 113 male, 55.54 ± 7.99 years). Significant differences in blood renalase concentrations between different SCORE thresholds were found. Significant correlations between blood renalase concentrations and systolic blood pressure, as well as between blood renalase concentrations and SCORE were found. A blood renalase concentration above 84.02 ng/ml was shown to be the most accurate predictor of a SCORE < 1%. In summary, it was documented that higher blood renalase concentrations were associated with lower cardiovascular risk assessed using the SCORE system.

Indexed as

Cardiovascular DiseasesMonoamine OxidaseAgedBlood PressureFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedPolandProspective StudiesRisk AssessmentRisk FactorsMonoamine OxidaserenalaseCardiovascular riskRenalaseSCORE

Identifiers

PMID41629438
PMCPMC12917144

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