Evidence map›Paper›PMID 41629220›Full record

ReviewCancer reports (Hoboken, N.J.)2026

Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report.

Minlian Nong, Weifeng Wei, Naijian Li, Yunxiang Zeng, Jinlin Wang

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minlian NongDepartment of Geriatrics Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Weifeng WeiDepartment of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.
Naijian LiDepartment of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.
Yunxiang ZengDepartment of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.
Jinlin WangDepartment of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.ORCID 0000-0003-0525-6649

Funding

National Major Science and Technology Project for Prevention and Treatment of Cancer, Cardiovascular and Cerebrovascular Diseases, Respiratory Diseases, and Metabolic Diseases 2024ZD0522800National Major Science and Technology Project for Prevention and Treatment of Cancer, Cardiovascular and Cerebrovascular Diseases, Respiratory Diseases, and Metabolic Diseases 2024ZD0522803Natural Science Foundation of China 82570134Natural Science Foundation of Guangdong Province 2025A1515012002Science and Technology Innovation Committee Joint Funding of Guangzhou 2023A03J0356
6 · The paper itself

Abstract

backgroundPrimary mediastinal malignant melanoma (PMMM) presenting with pleural effusion as the initial manifestation is exceedingly rare, presenting significant diagnostic and therapeutic challenges. This article reports a case of PMMM that initially manifested as pleural effusion and includes a review of the relevant literature. CASE: The patient was admitted with pleural effusion and an anterior mediastinal mass. A pleural biopsy and fine-needle aspiration of the mediastinal mass led to a pathological diagnosis of malignant melanoma. Ultimately, based on clinical findings, a final diagnosis of PMMM was established. The patient subsequently developed pleural hemorrhage; although hemostasis was achieved through thoracoscopy, his condition stabilized only temporarily. He ultimately succumbed to lung infection and multiple organ failure.

conclusionPMMM presenting with pleural effusion lacks distinct clinical features, highlighting the importance of pathological diagnosis. Pleural hemorrhage associated with pleural metastasis may be a characteristic feature, and the prognosis for such cases is poor. Enhanced recognition and early intervention are essential to improve outcomes.

Indexed as

Mediastinal NeoplasmsMelanomaPleural EffusionPleural Effusion, MalignantBiopsy, Fine-NeedleFatal OutcomeHemorrhageHumansMaleMiddle Aged

Identifiers

PMID41629220
PMCPMC12863993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.