Evidence map›Paper›PMID 41628795›Full record

ArticleExperimental hematology2026

Functional equivalence of γ- and x-ray irradiation for long-term peripheral blood chimerism and acute myeloid leukemia transplant outcomes in mice.

Shawn David, Griffin J Nye, Elizabeth Eudy, Ewelina Bolcun-Filas, Jennifer J Trowbridge, Kira A Young

Abstract read
In one paragraph

Article in Experimental hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shawn DavidGraduate School of Biomedical Science and Engineering, The University of Maine, Orono, ME; The Jackson Laboratory, Bar Harbor, ME.
Griffin J NyeThe Jackson Laboratory, Bar Harbor, ME.
Elizabeth EudyThe Jackson Laboratory, Bar Harbor, ME.
Ewelina Bolcun-FilasThe Jackson Laboratory, Bar Harbor, ME.
Jennifer J TrowbridgeThe Jackson Laboratory, Bar Harbor, ME. Electronic address: jennifer.trowbridge@jax.org.
Kira A YoungThe Jackson Laboratory, Bar Harbor, ME. Electronic address: kira.young@jax.org.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle AgeR01DK118072 · NIDDK · JACKSON LABORATORY · PI Jennifer Jean Trowbridge · 2018 to 2026
$4.2M
Inflammatory Signaling in DNMT3A-Mutated Human Hematopoietic Stem CellsU01AG077925 · NIA · JACKSON LABORATORY · PI LEVINE, ROSS L, TROWBRIDGE, JENNIFER JEAN · 2021 to 2025
$2.9M
Discovery of Aging-Associated Mechanisms Causing Expansion and Progression of Clonal Hematopoiesis of Indeterminant Potential (CHIP)R01AG069010 · NIA · JACKSON LABORATORY · PI TROWBRIDGE, JENNIFER JEAN · 2020 to 2024
$2.4M
Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle AgeR56DK118072 · NIDDK · JACKSON LABORATORY · PI TROWBRIDGE, JENNIFER JEAN · 2023 to 2023
$100k
NCI NIH HHS P30 CA034196NIA NIH HHS R01 AG069010NIA NIH HHS U01 AG077925NIDDK NIH HHS R01 DK118072NIDDK NIH HHS R56 DK118072
6 · The paper itself

Abstract

Total body irradiation is routinely used for myeloablation before a mouse hematopoietic cell transplant. Widespread transition from

Indexed as

Gamma RaysHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteTransplantation ChimeraAnimalsLeukocyte Common AntigensMiceMice, Inbred C57BLWhole-Body IrradiationX-RaysLeukocyte Common Antigens

Identifiers

PMID41628795
PMCPMC13045005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.