Evidence map›Paper›PMID 41628257›Full record

ArticleCirculation2026

Efficacy of Suppression of Serum Transthyretin With Patisiran and Vutrisiran in Variant ATTR Amyloidosis: An Observational Crossover Study.

Yousuf Razvi, Muhammad Umaid Rauf, Aldostefano Porcari, Josephine Mansell, Awais Sheikh, Adam Ioannou, Carol J Whelan, Lucia Venneri, Ana Martinez-Naharro, David F Hutt and 7 more

Abstract readLetter
In one paragraph

Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yousuf RazviNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0003-4766-3293
Muhammad Umaid RaufNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0001-8793-9333
Aldostefano PorcariNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0003-3307-0825
Josephine MansellNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0002-1778-3713
Awais SheikhNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0002-7707-226X
Adam IoannouNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0001-5017-8657
Carol J WhelanNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Lucia VenneriNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0009-0006-2551-7403
Ana Martinez-NaharroNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0003-3595-6988
David F HuttNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0002-3466-306X
Dorota RowczenioNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Janet A GilbertsonNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Ashutosh D WechalekarNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Helen J LachmannNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Philip N HawkinsNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0002-6983-9598
Marianna Fontana *National Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0002-9233-9831
Julian D Gillmore *National Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.ORCID 0000-0001-6174-9232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyloidcardiomyopathiesheart failureprealbuminRNA interferencetransthyretin

Identifiers

PMID41628257
PMCPMC12940623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.