ArticleMicrobiologyOpen2026
Rapid Typing of Extended-Spectrum β-Lactamase (ESBL)- and Metallo-β-Lactamase (MBL)-Producing Enterobacterales Using Fourier Transform Infrared (FT-IR) Spectroscopy.
Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
This study investigated the usefulness of the IR Biotyper, which types bacterial strains using Fourier transform infrared (FT-IR) spectroscopy, against extended-spectrum β-lactamase (ESBL)- and metallo-β-lactamase (MBL)-producing Enterobacterales. Sixty-six clinical isolates (20 ESBL-producing Klebsiella pneumoniae, 15 IMP-producing K. pneumoniae, and 31 IMP-producing Enterobacter cloacae complex isolates) were analyzed using the IR Biotyper, pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and whole-genome single-nucleotide polymorphism (wgSNP) analyses and the results were compared. Of the 20 ESBL-producing K. pneumoniae strains analyzed, the IR Biotyper detected three clusters. Of these clusters, two were determined as respective clusters by PFGE and wgSNP analyses, and the strains included in each cluster showed the same STs. The IR Biotyper detected three clusters in the analysis of 15 IMP-producing K. pneumoniae strains. Of these clusters, strains in the two clusters showed high concordance with PFGE, MLST, and wgSNP analyses. The IR Biotyper identified six clusters among the IMP-producing E. cloacae complex isolates. These results were fully concordant with those of PFGE, MLST, and wgSNP analyses in the two clusters. The range of adjusted Rand index was 0.734-0.967 between the IR Biotyper and PFGE and 0.658-0.857 between the IR Biotyper and MLST or wgSNP analyses. This study demonstrated the performance of IR Biotyper for the detection of clonal similarities in ESBL- and IMP-producing Enterobacterales and it might be useful for outbreak investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.