Assembly and Annotation of Kinetoplastid and Diplonemid Mitochondrial Genomes.

Evgeny S Gerasimov, Matus Valach, Gertraud Burger, Kristína Záhonová, Vyacheslav Yurchenko

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Evgeny S GerasimovFaculty of Biology, Lomonosov Moscow State University, Moscow, Russia.ORCID https://orcid.org/0000-0002-0497-1221

Matus ValachDepartment of Biochemistry and Robert-Cedergren Centre for Bioinformatics and Genomics, Université de Montréal, Montréal, Canada.ORCID https://orcid.org/0000-0001-8689-0080

Gertraud BurgerDepartment of Biochemistry and Robert-Cedergren Centre for Bioinformatics and Genomics, Université de Montréal, Montréal, Canada.ORCID https://orcid.org/0000-0002-8679-8812

Kristína ZáhonováLife Science Research Centre, Faculty of Science, University of Ostrava, Ostrava, Czechia.ORCID https://orcid.org/0000-0002-5766-0267

Vyacheslav YurchenkoLife Science Research Centre, Faculty of Science, University of Ostrava, Ostrava, Czechia. vyacheslav.yurchenko@osu.cz.ORCID https://orcid.org/0000-0003-4765-3263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This chapter outlines the assembly and annotation of mitochondrial genomes and transcriptomes of kinetoplastids and diplonemids using high-throughput sequencing data. The mitochondrial genomes of these protists are highly atypical, characterized by multipartition and extensive RNA editing. These complexities pose significant challenges for genome assembly, gene prediction, and transcript reconstruction. Here, we describe analytical strategies developed in our laboratories that address these issues.

Indexed as

Genome, MitochondrialKinetoplastidaMolecular Sequence AnnotationTrypanosomatinaHigh-Throughput Nucleotide SequencingRNA EditingTranscriptomeDiplonemidsKinetoplasteaMitochondrionNext-generation sequencingRNA editingTrypanosomatids

Identifiers

PMID41627735

DOI10.1007/978-1-0716-5142-1_9

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.