Evidence map›Paper›PMID 41627592›Full record

ArticleHead and neck pathology2026

Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus.

Akshay Trimukhe, Krushna Bhatt, Asit Ranjan Mridha, Varun Surya, Deepika Mishra, Rasla P C

Abstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akshay TrimukheDepartment of Oral Pathology and MicrobiologyCentre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Krushna BhattDepartment Of Oral and Maxillofacial Surgery, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Asit Ranjan MridhaDepartment Of Pathology, All India Institute Of Medical Sciences, New Delhi, India.
Varun SuryaDepartment of Oral Pathology and MicrobiologyCentre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India. drvarunsuryamds@aiims.edu.
Deepika MishraDepartment of Oral Pathology and MicrobiologyCentre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Rasla P CDepartment of Oral Pathology and MicrobiologyCentre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAspergillus species can induce calcium oxalate crystal deposition, serving as an important diagnostic marker when typical fruiting bodies or ancillary techniques are unavailable. CASE PRESENTATION: We report a 35-year-old male with recurrent oroantral fistula and maxillary sinus opacity. Histopathology demonstrated septate hyphae and birefringent calcium oxalate crystals under polarized light, confirming non-invasive aspergillosis.Oxalosis, frequently linked to Aspergillus niger, contributes to mucosal destruction through vascular compromise and oxidative injury.

conclusionRecognition of these crystals is crucial for differentiating Aspergillus from other filamentous fungi and underscores their diagnostic, pathogenic, and prognostic significance in sinonasal disease when conventional molecular methods are not employed.

Indexed as

AspergillosisCalcium OxalateMaxillary SinusAdultHumansMaleCalcium OxalateAspergillus nigerCalcium oxalate crystalsOxalosis

Identifiers

PMID41627592
PMCPMC12864617

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.