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ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Tibial shaft fractures with associated syndesmotic injury: a retrospective comparative analysis of 113 patients.

Varun Aysola, Jacob S Borgida, Robert K Wagner, Adam N Musick, Austin T Gregg, Derek van Duuren, Whitney H Smith, Carla H Lehle, Healy S Vise, Alice W Wong and 3 more

Abstract readComparative Study
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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Varun AysolaDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Jacob S BorgidaDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA. jborgida@bwh.harvard.edu.
Robert K WagnerDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Adam N MusickDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Austin T GreggDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Derek van DuurenDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Whitney H SmithDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Carla H LehleDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Healy S ViseDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Alice W WongDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Derek S StenquistDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Arun AnejaDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Thuan V LyDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to compare clinical outcomes following intramedullary nailing (IMN) of tibial shaft fractures with an associated, operatively treated distal syndesmotic injury to isolated tibial shaft fractures treated with IMN.

methodsPatients treated with IMN for a tibial shaft fracture with concomitant operative repair of a syndesmotic injury between 2010 and 2024 were identified from an institutional database of two Level 1 trauma centers. A comparison cohort of patients treated with IMN for isolated tibial shaft fractures was identified from a previously published database spanning 2021–2023. The primary outcome was the rate of postoperative complications (infection, reoperation, malunion, and nonunion).

resultsTwenty-four patients who underwent IMN for a tibial shaft fracture with concomitant operative repair of a syndesmotic injury and 89 patients who underwent IMN for an isolated tibial shaft fracture were identified. The overall median age was 39 years (IQR: 28–55), 60 patients (53%) were male, and 34 (30%) fractures were open. Patient and injury characteristics were not significantly different between groups. Patients with associated syndesmotic injury were recommended non-weightbearing more often (79% vs. 36%, p < 0.001). Patients with concomitant operative repair of a syndesmotic injury had 3.9-fold increased odds of undergoing symptomatic implant removal compared to isolated injuries (95% CI 1.14–13.2, p = 0.027). Odds of reoperation for deep and superficial infection, and rates of nonunion and malunion were similar between groups.

conclusionsPatients undergoing intramedullary nailing for tibial shaft fractures with an associated, operatively treated distal syndesmotic injury should be educated on the higher odds of undergoing implant removal compared to isolated tibial shaft fractures. The observed rate of implant removal was similar to those reported following syndesmotic fixation for ankle injuries. Other complication rates, including nonunion, malunion, and infection, were similar.

Indexed as

Ankle InjuriesFracture Fixation, IntramedullaryPostoperative ComplicationsTibial FracturesAdultFemaleHardware RemovalHumansMaleMiddle AgedReoperationRetrospective StudiesReoperationSyndesmosisSyndesmotic injuryTibial shaft

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.