Evidence map›Paper›PMID 41627554›Full record

ArticleJournal of molecular neuroscience : MN2026

Unlocking Stress Coping Mechanisms: Implications for Salivary Antioxidant Defense and Trace Element Homeostasis.

Galina V Portnova, Elena V Proskurnina, Krystsina Liaukovich, Ivan V Mikheev, Grigoriy R Chermashentsev, Evgeniia I Alshanskaia, Olga V Martynova

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Article in Journal of molecular neuroscience : MN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Galina V PortnovaLaboratory of Human Higher Nervous Activity, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, 117485, Russia. caviter@list.ru.
Elena V ProskurninaFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Lytkino village (Solnechnogorsk u.d., Moscow region), Moscow, 141534, Russia.
Krystsina LiaukovichLaboratory of Human Higher Nervous Activity, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, 117485, Russia.
Ivan V MikheevDepartment of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Grigoriy R ChermashentsevDepartment of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Evgeniia I AlshanskaiaInstitute of Cognitive Neuroscience, HSE University, Moscow, 101000, Russia.
Olga V MartynovaLaboratory of Human Higher Nervous Activity, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, 117485, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the relationship between stress coping ability, salivary antioxidant capacity (AOC), and trace element concentrations, focusing on zinc (Zn) and potassium (K). A cohort of 73 participants, divided into groups based on stress coping ability (SCA) ("adaptive", "intermediate", and "maladaptive"), underwent cognitive tasks while physiological and behavioral data were collected. Saliva samples were analyzed for AOC and trace elements, including Zn, K, total phosphorus (P), and total sulfur (S). Results revealed that individuals with effective stress coping strategies (the "adaptive" group) exhibited significantly higher AOC and Zn levels, along with lower K levels, compared to those with maladaptive coping abilities. Positive correlations were observed between Zn and AOC, while K showed a negative correlation with AOC. Behavioral data indicated that the "maladaptive" group demonstrated a pronounced decline in self-assessment as task difficulty increased, despite similar task performance across groups. These findings suggest that stress coping ability is a stable trait influencing physiological homeostasis, with effective coping associated with enhanced antioxidant defenses and balanced trace element regulation. The study highlights the importance of stress management in maintaining oxidative balance and emotional resilience, offering potential pathways for interventions targeting stress-related physiological and cognitive dysregulation.

Indexed as

Adaptation, PsychologicalAntioxidantsSalivaStress, PsychologicalTrace ElementsAdultCoping SkillsFemaleHomeostasisHumansMalePotassiumZincAntioxidantsPotassiumTrace ElementsZincCognitive loadSalivary antioxidant capacity (AOC)Salivary trace elementsStress coping ability

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.