Evidence map›Paper›PMID 41627486›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Increased risk of knee osteoarthritis progressing to total knee arthroplasty following patella fractures: an age stratified population analysis.

Daniel E Pereira, Zachary D Randall, Mitchell S Mologne, Mitchel R Obey, Jenna-Leigh Wilson, Christopher M McAndrew, Marschall B Berkes

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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Daniel E PereiraDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA. d.e.pereira@wustl.edu.
Zachary D RandallDepartment of Orthopedics, University of California, Davis, Sacramento, USA.
Mitchell S MologneDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA.
Mitchel R ObeyDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA.
Jenna-Leigh WilsonDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA.
Christopher M McAndrewDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA.
Marschall B BerkesDepartment of Orthopedics, Washington University in St. Louis, St Louis, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatella fractures are articular injuries that can alter knee biomechanics, disrupt joint contact forces, and promote cartilage degeneration. However, progression to reconstructive surgery is not fully characterized. This study investigates the risk of progression to total knee arthroplasty (TKA) following patella fractures and assesses whether initial operative versus nonoperative management impacts this risk.

methodsWe retrospectively analyzed TKA progression in patients with patella fractures using synthetic data from a large Level I academic trauma center (1996-2024). Patients were identified by historic diagnostic codes for patella fractures and TKA. Age-stratified TKA rates were compared to published national data, and indirect standardization was used to calculate the age-adjusted standardized incidence ratio (SIR), risk difference (RD), and attributable risk percent (AR%).

resultsAmong 3212 native patella fractures, 263 patients (8.2%) later underwent TKA. The mean age at fracture was 58.1 years (SD 17.5) with a mean time to TKA of 4.1 years (SD 4.9). The SIR for TKA was 1.6 (95% CI 1.3-1.9), RD 3.1%, and AR% 37.2%. In the 406 operatively treated fractures (mean age 55.3 years, SD 18.6; 60.8% female), TKA occurred in 5.4% (SIR 1.4, 95% CI 0.9-2.2), compared to 8.6% in the 2,806 nonoperatively treated fractures (mean age 58.5 years, SD 17.4; 61.8% female; SIR 2.1, 95% CI 1.8-2.3) (p = 0.04).

conclusionIndividuals with patella fractures face an increased lifetime risk of advanced joint degeneration and subsequent TKA compared to the general population, with nonoperative treatment linked to a higher risk than operative management. Further analysis of initial injury patterns, radiographic findings, and patient factors are in need for further research to understand and validate these findings.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneePatellaPatella FractureAdultAgedAge FactorsDisease ProgressionFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsOpen reduction internal reductionOrthopaedic traumaPatella fracturePost-traumatic arthritisTotal knee arthroplasty

Identifiers

PMID41627486
PMCPMC12864205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.