ReviewArchives of microbiology2026
The structures and functions of Salmonella outer membrane.
Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Development and evaluation of a multi-epitope subunit vaccine against Salmonella Enteritidis infection.Poultry science · 2026Article
- Structure and function of Salmonella inner membrane.Archives of microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
The outer membrane (OM) of Salmonella is a complex, asymmetric, and dynamic barrier that is essential for Salmonella survival, pathogenicity, and antimicrobial resistance. This review comprehensively summarizes the structures and functions of the three principal components of the Salmonella outer membrane, namely proteins, lipopolysaccharides, and phospholipids. Outer membrane proteins can be classified into five major functional categories. (1) Structural maintenance and assembly proteins, such as outer membrane protein A and the β-barrel assembly machinery complex, are critical for maintaining outer membrane integrity. (2) Transport channel proteins, including the general porin OmpC and the substrate-specific channel LamB, facilitate the passive diffusion of small molecules. (3) TonB-dependent transport systems, such as FepA and FhuA, mediate the active uptake of essential nutrients, particularly iron. (4) Proteins with catalytic and metabolic activities, including PagP and PgtE, are involved in lipid modification and membrane remodeling. (5) Virulence-associated proteins, such as PagC, PagN, and Rck, play key roles in bacterial adhesion to and invasion of host cells. The lipopolysaccharides of Salmonella consists of three distinct structural domains: (1) lipid A, which constitutes the endotoxic core and is regulated by the PhoP/PhoQ two-component regulatory system; (2) the core polysaccharide, which serves a structural linking function; and (3) the O-antigen, which determines serotype specificity and contributes to immune evasion. In addition, the outer membrane phospholipids-primarily phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin-are essential for maintaining membrane fluidity, stability, and lipid asymmetry. Overall, this review provides an integrated overview of the molecular structures and biological functions of the Salmonella outer membrane, offering a theoretical foundation for the development of novel antibacterial drugs and vaccines.
Indexed as
Identifiers
41627475What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.