Evidence map›Paper›PMID 41627455›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Possible detrimental effects of postponed intubation during interhospital transfer of severely brain injured patients: retrospective analysis of the Traumaregister DGU

Ferdinand C Wagner, Daniel Witry, Rolf Lefering, Christoph Scholz, Hagen Schmal, Jörg Bayer

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ferdinand C WagnerDepartment of Orthopaedic and Trauma Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Daniel WitryDepartment of Trauma and Orthopaedic Surgery, Schwarzwald-Baar Hospital, Klinikstraße 11, Villingen-Schwenningen, 78052, Germany.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), Faculty of Health, University Witten/Herdecke, Ostmerheimer Straße 200, Cologne, 51109, Germany.
Christoph ScholzDepartment of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 64, Freiburg, 79106, Germany.
Hagen SchmalDepartment of Orthopaedic and Trauma Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Jörg BayerDepartment of Orthopaedic and Trauma Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany. joerg.bayer@klinikum.uni-freiburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrehospitally, the paradigm of obliged intubation in traumatic brain injured (TBI) patients with a reduced Glasgow Coma Scale (GCS) < 9 has been debated. Many patients with severe TBI need interhospital transfer to definitive care, so we sought to elucidate possible disadvantages for patients with a reduced level of consciousness where intubation prior transportation was withheld.

methodsTransferred patients with at least serious blunt injury to the head (Abbreviated Injury Scale

resultsComparing spontaneously breathing versus already intubated patients (ITN) at admission we did not find statistically significant differences in mortality (33.2% vs. 20.4%; p = 0.067), multiple organ failure (MOF) (37.1% vs. 34%; p = 0.667) or sepsis rates (13.6% vs. 4.2%; p = 0.069). Multiple regression analysis for mortality revealed only age > 70 years, coagulopathy and AIS

conclusionOur results may suggest an inferior outcome when intubation in patients with GCS 4-9 is needed during admission at the receiving hospital. Further research is warranted to scrutinize optimal airway management for interhospital transfer of TBI patients with reduced GCS.

Indexed as

Brain Injuries, TraumaticIntubation, IntratrachealPatient TransferAdultAgedFemaleGlasgow Coma ScaleHumansMaleMiddle AgedMultiple Organ FailureRegistriesRetrospective StudiesAirway managementEmergency department managementNeurotrauma centerTraumatic brain injury

Identifiers

PMID41627455
PMCPMC12864293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.