ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
Dose-response relationship between enhanced recovery protocol adherence and outcomes in geriatric spine metastasis surgery.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to test the hypothesis that a dose-response relationship exists between adherence to Enhanced Recovery After Surgery (ERAS) protocols and postoperative outcomes in geriatric patients undergoing separation surgery for spinal metastases.
methodsIn a single-center retrospective cohort study, 128 patients aged ≥ 70 years undergoing elective separation surgery for symptomatic spinal metastases (2020-2023) were included. Adherence to eight core ERAS components was assessed, and an overall adherence score was calculated. The primary outcome was composite complications (Clavien-Dindo Grade ≥ II) within 30 days. Multivariable logistic regression, adjusted for frailty and preoperative albumin, analyzed the association between adherence and outcomes.
resultsMedian ERAS adherence was 75%. Each 10% increase in adherence was independently associated with 31% lower odds of major complications (aOR = 0.69; 95% CI: 0.55-0.88; p = 0.002). The High-Adherence group (≥ 75% adherence) experienced significantly shorter length of stay (5 vs. 7 days, p < 0.001) and better pain control at discharge (median VAS 2 vs. 3, p < 0.001) compared to the Low-Adherence group.
conclusionOur analysis suggests a significant dose-response relationship between ERAS adherence and improved outcomes in geriatric spine metastasis surgery. Higher adherence was independently associated with lower odds of major complications and shorter recovery time, thereby supporting the concept of a "Precision ERAS" approach.
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