Evidence map›Paper›PMID 41627417›Full record

ArticleSurgery today2026

Treatment of uncomplicated appendicitis: is interval appendectomy an effective strategy?

Kohki Takeda, Takeshi Yamada, Ryo Ohta, Kay Uehara, Akihisa Matsuda, Seiichi Shinji, Yasuyuki Yokoyama, Goro Takahashi, Takuma Iwai, Koki Hayashi and 1 more

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kohki TakedaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. take-yokohama@nms.ac.jp.
Takeshi YamadaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Ryo OhtaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Kay UeharaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Akihisa MatsudaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Seiichi ShinjiDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Yasuyuki YokoyamaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Goro TakahashiDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Takuma IwaiDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Koki HayashiDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Hiroshi YoshidaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe benefits of interval appendectomy (IA) in complicated appendicitis are well known. However, these remain unclear in uncomplicated appendicitis (UA) despite patients with UA often receiving IA in actual clinical situations. This study investigated whether IA is an effective strategy for the treatment of UA.

methodsWe included Patients diagnosed with UA who underwent laparoscopic surgery between January 2017 and December 2023 were included. We compared the surgical outcomes between the emergency surgery (ES) and IA groups and analyzed 12 factors to identify risk factors for postoperative complications.

results263 patients (ES group, N = 161; IA group, N = 102) were enrolled. The rates of any complication, Clavien-Dindo (C-D) grade ≥ I, and severe complication, C-D grade ≥ III, were similar (P = 0.38, P = 0.26) in both groups. In contrast, the total length of hospital stay was shorter in the ES group (P < 0.001). Among the 263 patients, postoperative complications of any type were observed in 14 (5.3%). A multivariate analysis identified no independent risk factors for postoperative complications including ES.

conclusionThe surgical outcomes of ES in patients with UA were favorable. Therefore, the benefits of IA are minimal and it may not be the first therapeutic choice for UA.

Indexed as

AppendectomyAppendicitisLaparoscopyAdultFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRisk FactorsTime FactorsTreatment OutcomeAppendicitisEmergency surgeryInterval appendectomyPostoperative complicationsUncomplicated appendicitis

Identifiers

PMID41627417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.