Evidence map›Paper›PMID 41627063›Full record

ReviewEmerging topics in life sciences2026

Cytochrome nanowires under electron microscopy.

Holly A Petersen, Allon I Hochbaum, Daniel R Bond, Fengbin Wang

Abstract readReview
In one paragraph

Review in Emerging topics in life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Holly A PetersenDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35233, U.S.A.
Allon I HochbaumDepartment of Chemical and Biomolecular Engineering, Materials Science and Engineering, Chemistry, and Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, U.S.A.
Daniel R BondDepartment of Plant and Microbial Biology, and BioTechnology Institute, University of Minnesota, Saint Paul, MN 55455, U.S.A.
Fengbin WangDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35233, U.S.A.ORCID 0000-0003-1008-663X

Funding

Investigating and Utilizing Microbial AppendagesR35GM159704 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Fengbin Wang · 2025 to 2026
$817k
NIGMS NIH HHS R35 GM159704
6 · The paper itself

Abstract

Microbial nanowires are appendages that Bacteria and Archaea use to transfer electrons to external surfaces, such as minerals, electrodes, or other microbes. While initial studies suggested that nanowires were modified pili, recent advancements in cryo-EM revealed that microbial nanowires are composed of multi-heme c-type cytochromes. In this review, we discuss the discovery of microbial nanowires, advancements that allowed elucidation of their near-atomic resolution cryo-EM structures, and the impact of heme arrangement on electron transfer. We also discuss how new structural information can be used to identify filaments in images from published literature. The structural insights gained from these studies provide a deeper understanding of the mechanisms underlying long-range electron transport in microbial nanowires and their potential applications in bioelectronics and energy-generating microbial fuel cells.

Indexed as

Cryoelectron MicroscopyCytochromesNanowiresBacteriaElectron TransportHemeCytochromesHemecryo-EMcytochrome nanowiresextracellular electron transferhelical filamentmicrobial nanowires

Identifiers

PMID41627063
PMCPMC12954529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.