Evidence map›Paper›PMID 41626888›Full record

ArticleResearch synthesis methods2026

What can we learn from 1,000 meta-analyses across 10 different disciplines?

Weilun Wu, Jianhua Duan, W Robert Reed, Elizabeth Tipton

Abstract read
In one paragraph

Article in Research synthesis methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weilun WuDepartment of Economics and Finance and UCMeta, University of Canterbury, Christchurch, New Zealand.
Jianhua Duanhttps://ror.org/055qjgz33Statistics New Zealand, Christchurch, New Zealand.
W Robert ReedDepartment of Economics and Finance and UCMeta, University of Canterbury, Christchurch, New Zealand.
Elizabeth TiptonStatistics for Evidence-Based Policy and Practice Center, https://ror.org/000e0be47Northwestern University, Evanston, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study analyzes 1,000 meta-analyses drawn from 10 disciplines-including medicine, psychology, education, biology, and economics-to document and compare methodological practices across fields. We find large differences in the size of meta-analyses, the number of effect sizes per study, and the types of effect sizes used. Disciplines also vary in their use of unpublished studies, the frequency and type of tests for publication bias, and whether they attempt to correct for it. Notably, many meta-analyses include multiple effect sizes from the same study, yet fail to account for statistical dependence in their analyses. We document the limited use of advanced methods-such as multilevel models and cluster-adjusted standard errors-that can accommodate dependent data structures. Correlations are frequently used as effect sizes in some disciplines, yet researchers often fail to address the methodological issues this introduces, including biased weighting and misleading tests for publication bias. We also find that meta-regression is underutilized, even when sample sizes are large enough to support it. This work serves as a resource for researchers conducting their first meta-analyses, as a benchmark for researchers designing simulation experiments, and as a reference for applied meta-analysts aiming to improve their methodological practices.

Indexed as

Meta-Analysis as TopicAlgorithmsCluster AnalysisComputer SimulationData Interpretation, StatisticalHumansModels, StatisticalPsychologyPublication BiasRegression AnalysisResearch DesignSample Sizeclusteringinterdisciplinary comparisonmeta-analysismeta-analytic estimatorsmeta-regressiontests for publication bias

Identifiers

PMID41626888
PMCPMC12823205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.