Evidence map›Paper›PMID 41626876›Full record

ArticleGenome biology and evolution2026

ERGA-BGE Genomes of Culex laticinctus, Culex modestus, Culex perexiguus, and Culex theileri: Unveiling the Genomes of the Key Vectors of West Nile Virus in the Mediterranean Basin.

María José Ruiz-López, Sonia Cebrián-Camisón, Iker Irisarri, Sergio Magallanes, Josué Martínez-de la Puente, Jordi Figuerola, Robert M Waterhouse, Wellcome Sanger Institute Tree Of Life Management Samples And Laboratory Team, Wellcome Sanger Institute Scientific Operations Sequencing Operations, Wellcome Sanger Institute Tree Of Life Core Informatics Team and 3 more

Abstract read
In one paragraph

Article in Genome biology and evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

María José Ruiz-LópezDepartamento de Biología de la Conservación y Cambio Global, Estación Biológica de Doñana (EBD), CSIC, Seville 41092, Spain.ORCID 0000-0002-6849-644X
Sonia Cebrián-CamisónDepartamento de Biología de la Conservación y Cambio Global, Estación Biológica de Doñana (EBD), CSIC, Seville 41092, Spain.ORCID 0000-0002-6591-1054
Iker IrisarriDepartamento de Biodiversidad y Biología Evolutiva, Museo Nacional de Ciencias Naturales-CSIC, Madrid 28006, Spain.ORCID 0000-0002-3628-1137
Sergio MagallanesDepartamento de Biología de la Conservación y Cambio Global, Estación Biológica de Doñana (EBD), CSIC, Seville 41092, Spain.ORCID 0000-0002-6748-9547
Josué Martínez-de la PuenteDepartamento de Biología de la Conservación y Cambio Global, Estación Biológica de Doñana (EBD), CSIC, Seville 41092, Spain.ORCID 0000-0001-8055-4115
Jordi FiguerolaDepartamento de Biología de la Conservación y Cambio Global, Estación Biológica de Doñana (EBD), CSIC, Seville 41092, Spain.ORCID 0000-0002-4664-9011
Robert M WaterhouseEnvironmental Bioinformatics Group, SIB Swiss Institute of Bioinformatics, Batiment Amphipole, UNIL-Sorge, Lausanne 1015, Switzerland.ORCID 0000-0003-4199-9052
Wellcome Sanger Institute Tree Of Life Management Samples And Laboratory TeamTree of Life, Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Wellcome Sanger Institute Scientific Operations Sequencing OperationsTree of Life, Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Wellcome Sanger Institute Tree Of Life Core Informatics TeamTree of Life, Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Leanne HaggertyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.ORCID 0000-0001-8843-3596
Fergal MartinEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.ORCID 0000-0002-1672-050X
Tom BrownDepartment of Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany.ORCID 0000-0001-8293-4816

Funding

Biodiversity, Circular Economy and EnvironmentDepartment for Business, Energy and Industrial Strategy's Horizon Europe Guarantee SchemeSpanish State Research AgencySwiss State Secretariat for Education, Research and InnovationUK Research and Innovation
6 · The paper itself

Abstract

The reference genomes of Culex laticinctus, Culex modestus, Culex perexiguus, and Culex theileri offer crucial resources for exploring the genetic basis of vector competence for different pathogens, including the emerging West Nile virus. Each genome was assembled into three contiguous chromosomal pseudomolecules. These chromosome-level assemblies encompass 834, 698, 436, and 934 Mb, respectively. They are composed of 3,284, 4,220, 1,917, and 2,704 contigs and 312, 979, 475, and 709 scaffolds, with contig N50 values of 434, 313, 473, and 770 kb, and scaffold N50 values of 292, 246, 150, and 281 Mb, respectively. These genomes offer an essential genomic resource for advancing our understanding of Culex evolution and population genomic analyses, which will help to implement sustainable mosquito control efforts and disease prevention.

Indexed as

CulexGenome, InsectMosquito VectorsAnimalsMediterranean RegionWest Nile FeverWest Nile virusbiodiversity genomics EuropeCulexCulicidaeEarth BioGenome projectEuropean reference genome atlasmosquito genome

Identifiers

PMID41626876
PMCPMC12862641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.