Evidence map›Paper›PMID 41626560›Full record

ReviewJournal of pharmaceutical analysis2026

Recent advances in nanomaterial-based optical biosensors and their biomedical and biopharmaceutical applications.

Mengjia Xu, Lutfun Nahar, Kenneth J Ritchie, Chenxu Wang, Li Cheng, Zimiao Wu, Satyajit D Sarker, Mingquan Guo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. MoSRSC advances · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengjia XuNingbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Zhejiang International Cooperation Base of Biomedical Materials Technology and Application, Ningbo Cixi Institute of Biomedical Engineering, Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, Zhejiang, 315201, China.
Lutfun NaharLaboratory of Growth Regulators, Palacký University and Institute of Experimental Botany, The Czech Academy of Sciences, Olomouc, 78371, Czech Republic.
Kenneth J RitchieCentre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK.
Chenxu WangNingbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Zhejiang International Cooperation Base of Biomedical Materials Technology and Application, Ningbo Cixi Institute of Biomedical Engineering, Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, Zhejiang, 315201, China.
Li ChengAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo, Zhejiang, 315300, China.
Zimiao WuAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo, Zhejiang, 315300, China.
Satyajit D SarkerCentre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK.
Mingquan GuoNingbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Zhejiang International Cooperation Base of Biomedical Materials Technology and Application, Ningbo Cixi Institute of Biomedical Engineering, Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, Zhejiang, 315201, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical biosensors are gaining popularity owing to their portability, miniaturization, no requirement for additional attachments, and rapid responsiveness. These features render them suitable for various applications including at-home diagnostics, pharmacology, and continuous molecular monitoring. The integration of functionalized low-dimensional nanomaterials (zero-dimensional (0D), 1D, 2D, and 3D) has redirected focus towards the design, fabrication, and optimization of optical biosensors. This review summarizes the fundamental mechanisms underlying optical biosensing. The key mechanisms include localized surface plasmon resonance (LSPR), photoluminescence (PL), surface enhancement Raman scattering (SERS), nanozyme-based colorimetric strategies, chemiluminescence, bioluminescence, and electrochemiluminescence. The advantages of various low-dimensional nanomaterials for different types of optical biosensors are presented. This comparison emphasizes their potential superiority in targeted biosensing applications. Therefore, promoting optical biosensing techniques and recent developments in advanced biosensing strategies for biomedical research and biopharmaceutical applications are necessary to establish their future directions.

Indexed as

At-home diagnosticsBiopharmaceutical applicationsContinuous molecular monitoringFundamental mechanisms for biosensingLow-dimensional nanomaterialsOptical biosensors

Identifiers

PMID41626560
PMCPMC12856604

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.