Evidence map›Paper›PMID 41626505›Full record

ArticleACS omega2026

Pilot-Scale Continuous Flow Synthesis of Capsaicinoids and Their Formulation with Cyclodextrins.

Bettina Rávai, Dóra V Ujj, Máté J Orosz, Ecaterina Revenco, Szabolcs Béni, Ádám Tajti, Erika Bálint

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bettina RávaiDepartment of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.
Dóra V UjjDepartment of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.
Máté J OroszDepartment of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.
Ecaterina RevencoDepartment of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.
Szabolcs BéniDepartment of Analytical Chemistry, Faculty of Science, Eötvös Loránd University, Pázmány Péter Sétány 1/a., H-1117 Budapest, Hungary.
Ádám TajtiBálint Analitika Ltd., Kondorfa u. 6., H-1116 Budapest, Hungary.
Erika BálintDepartment of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.ORCID https://orcid.org/0000-0002-5107-7089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capsaicinoids are the principal compounds responsible for the pungency of chili peppers and are widely used as food additives as well as in pharmaceutical and cosmetic formulations or potential agrochemicals. However, capsaicin and its derivatives have poor aqueous solubility, which limits their broader application. In this study, we report the first pilot-scale continuous flow synthesis of capsaicin, dihydrocapsaicin, and nonivamide, using sequential oxime formation, hydrogenation, and

Identifiers

PMID41626505
PMCPMC12854497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.