Evidence map›Paper›PMID 41626383›Full record

SynthesisFrontiers in public health2025

Arterial stiffness adaptations to chronic resistance and aerobic exercise: a systematic review of exercise modalities.

Ina Shaw, Musa L Mathunjwa, Jane Black, Razieh Khanmohammadi, Takalani Clearance Muluvhu, Gregory A Brown, Gudani G Mukoma, Brandon S Shaw

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ina ShawSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, United Kingdom.
Musa L MathunjwaDepartment of Human Movement Science, University of Zululand, KwaDlangezwa, South Africa.
Jane BlackSchool of Health and Sports Sciences, University of Suffolk, Ipswich, United Kingdom.
Razieh KhanmohammadiDepartment of Sports Science, Urmia University, Urmia, Iran.
Takalani Clearance MuluvhuDepartment of Sport, Rehabilitation and Dental Sciences, Tshwane University of Technology, Pretoria, South Africa.
Gregory A BrownPhysical Activity and Wellness Laboratory, Department of Kinesiology and Sports Science, University of Nebraska at Kearney, Kearney, NE, United States.
Gudani G MukomaDepartment of Biokinetics, Recreation and Sport Science, Faculty of Health Sciences, University of Venda, Thohoyandou, South Africa.
Brandon S ShawSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Arterial stiffness is a strong predictor of cardiovascular morbidity and mortality, especially in older adults. Despite exercise being shown to positively influence arterial health, the relative effectiveness of various exercise modalities remains unclear. Objectives: This systematic review aimed to examine the effects of resistance training (RT), aerobic training (AER), and concurrent aerobic plus resistance training (CON) on arterial stiffness in older adults, a recognised modifiable and independent cardiovascular risk factor. Methods: A comprehensive search of Medline (EBSCO), EMBASE, the Cochrane Database of Systematic Reviews, and clinicaltrials.gov was conducted. The robust search strategy, which also included systematic reviews being hand-searched for relevant articles and a forward and backwards citation search on the included articles, was employed to reduce the risk of selection and publication biases. Studies included in the review assessed arterial stiffness using pulse wave velocity (PWV) and focused on individuals aged 60 years and above who participated in a chronic (≥ 8 weeks) structured exercise intervention (RT, AER, or CON). Only randomised controlled trials were included. Sixteen studies met the inclusion criteria, and their methodological quality was evaluated using the PEDro scale. Results: The findings indicated that resistance training generally had a neutral effect (mean difference, MD: 0.06 m/s. SD: ±0.45) on arterial stiffness, whilst aerobic training produced modest improvements (MD: -0.62 m/s, SD: ±0.51). Notably, concurrent training consistently reduced arterial stiffness across diverse older adult(s) populations (MD: -0.85 m/s, SD: ±0.63). Conclusion: Combined aerobic and resistance training is the most effective non-pharmacological strategy for reducing arterial stiffness in older adults. This approach may offer essential benefits for cardiovascular health and healthy ageing. Further long-term studies are needed to explore the mechanisms involved and to inform tailored exercise interventions in geriatric populations.

Indexed as

Adaptation, PhysiologicalExerciseResistance TrainingVascular StiffnessAgedHumansPulse Wave Analysisendotheliumexercisehemodynamicsolder adult(s)pulse wave velocityvascular stiffness

Identifiers

PMID41626383
PMCPMC12851956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.